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. 2024 Jan 15;9(1):13.
doi: 10.3390/geriatrics9010013.

Prognostic Determinants of Anterior Large Vessel Occlusion in Acute Stroke in Elderly Patients

Takashi Mitsuhashi  1 , Kohsuke Teranishi  2 , Joji Tokugawa  1 , Takumi Mitsuhashi  1 , Makoto Hishii  1 , Hidenori Oishi  2
Affiliations

Prognostic Determinants of Anterior Large Vessel Occlusion in Acute Stroke in Elderly Patients

Takashi Mitsuhashi et al. Geriatrics (Basel). .

Abstract

This study investigated prognostic factors in elderly patients (80 years and older) undergoing mechanical thrombectomy (MT) for anterior circulation large vessel occlusion (LVO) in acute stroke treatment. Of 59 cases, 47.5% achieved a favorable outcome (mRS ≤ 3) at three months, with a mortality rate of 20.3%. Factors associated with better outcomes included younger age, lower admission National Institute of Health Stroke Scale (NIHSS) scores, lower N-terminal pro-brain natriuretic peptide (NT-proBNP) and D-dimer levels, the presence of the first pass effect (FPE), and successful recanalization. However, logistic regression showed that only lower admission NIHSS scores were significantly correlated with favorable outcomes. In addition, this study suggests that lower admission NT-proBNP and D-dimer levels could potentially serve as prognostic indicators for elderly LVO patients undergoing MT.

Keywords: elderly; large vessel occlusion; mechanical thrombectomy; prognosis.

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Conflict of interest statement

The authors declare no conflict of interest.

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