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Review
. 2023 Dec 28;14(1):52-68.
doi: 10.3390/clinpract14010006.

Factors Contributing to Surgical Site Infections: A Comprehensive Systematic Review of Etiology and Risk Factors

Alexandra Bucataru  1   2 , Maria Balasoiu  3 , Alice Elena Ghenea  3 , Ovidiu Mircea Zlatian  3 , Dan Dumitru Vulcanescu  4   5 , Florin George Horhat  4   5 , Iulia Cristina Bagiu  4   5 , Virgiliu Bogdan Sorop  6 , Madalina Ioana Sorop  7 , Andrada Oprisoni  8 , Estera Boeriu  8 , Stelian Stefanita Mogoanta  9   10
Affiliations
Review

Factors Contributing to Surgical Site Infections: A Comprehensive Systematic Review of Etiology and Risk Factors

Alexandra Bucataru et al. Clin Pract. .

Abstract

Surgical site infections persist as a substantial concern within the realm of hospital-acquired infections. This enduring issue is further compounded by the mounting challenge of antibiotic resistance, a surge in surgical interventions, and the presence of comorbidities among patients. Thus, a comprehensive exploration of all discernible risk factors, as well as proactive preventive and prophylactic strategies, becomes imperative. Moreover, the prevalence of multidrug-resistant microorganisms has reached alarming proportions. Consequently, there is an acute need to investigate and scrutinize all potential therapeutic interventions to counter this burgeoning threat. Consequently, the primary objective of this review is to meticulously assess the origins and risk elements intertwined with surgical site infections across a diverse spectrum of surgical procedures. As the medical landscape continues to evolve, this critical analysis seeks to provide a nuanced understanding of the multi-faceted factors contributing to surgical site infections, with the overarching aim of facilitating more effective management and mitigation strategies. By exploring these dimensions comprehensively, we endeavor to enhance patient safety and the quality of surgical care in this era of evolving healthcare challenges.

Keywords: antimicrobial resistance; risk factors; surgical site infections (SSIs).

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
Operative risk assessment flowchart.
Figure 2
Figure 2
PRISMA flow diagram of the study selection process.
See this image and copyright information in PMC

References

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