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Review
. 2023 Dec 26;14(1):32.
doi: 10.3390/jpm14010032.

Emerging Perspectives on the Set of Conditions That Lead to the Emergence of Metabolic Syndrome

Bogdan M Tarcău  1 , Laura G Vicaș  2 , Lorena Filip  3 , Florin Maghiar  4 , Mircea Șandor  5 , Annamaria Pallag  2 , Tunde Jurca  2 , Mariana Eugenia Mureșan  6 , Eleonora Marian  2
Affiliations
Review

Emerging Perspectives on the Set of Conditions That Lead to the Emergence of Metabolic Syndrome

Bogdan M Tarcău et al. J Pers Med. .

Abstract

Metabolic syndrome, as a medical condition, presents multifactorial complexity that is characterized by the resulting damage from genetic, environmental, and lifestyle factors (presence or absence of physical activity, food choices). Thus, metabolic syndrome qualifies unequivocally as a medical condition in which there are, simultaneously, several independent metabolic risk factors, namely, abdominal obesity, high triglyceride level, low HDL cholesterol level, arterial hypertension, and high glycemic level. Although age, sex, socio-economic status, and the precise definition of metabolic syndrome all influence the prevalence and risk of developing the condition, clinical and epidemiological studies clearly show that central obesity, as measured by an increased abdominal circumference, is the main risk factor. Thus, due to the growing global incidence of obesity, there has been an increase in the incidence of metabolic syndrome. Starting with obesity, all other metabolic risk factors are influenced: for example, as a result of insulin resistance with hyperglycemia, diabetes is linked to an increased risk of cardiovascular disease due to increased abdominal circumference. Through this review, we aimed to highlight the latest research studies and dietary nutritional interventions useful in the prevention of this disease but also implementation strategies for primary prevention among the healthy population.

Keywords: diet interventions; dyslipidemia; hyperglycemia; hypertriglyceridemia; metabolic syndrome.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
Trends in the quantity of papers and reviews pertaining to metabolic syndrome and dietary therapies across time [9].
Figure 2
Figure 2
Scientific publications categorized and included in the Scopus database [9].
Figure 3
Figure 3
The Prisma flow diagram outlines the selection procedure for bibliographic references.
Figure 4
Figure 4
The mechanism of C-reactive protein.
Figure 5
Figure 5
The metabolism of fat.
Figure 6
Figure 6
Genetic factors and the risk of altering the clinical parameters [54,55].
See this image and copyright information in PMC

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