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Review
. 2024 Jan 18;11(1):29.
doi: 10.3390/jcdd11010029.

Developments and Challenges in Durable Ventricular Assist Device Technology: A Comprehensive Review with a Focus on Advancements in China

Jingrong Tu  1 , Li Xu  1 , Fei Li  1   2 , Nianguo Dong  1
Affiliations
Review

Developments and Challenges in Durable Ventricular Assist Device Technology: A Comprehensive Review with a Focus on Advancements in China

Jingrong Tu et al. J Cardiovasc Dev Dis. .

Abstract

Heart transplantation is currently the most effective treatment for end-stage heart failure; however, the shortage in donor hearts constrains the undertaking of transplantation. Mechanical circulatory support (MCS) technology has made rapid progress in recent years, providing diverse therapeutic options and alleviating the dilemma of donor heart shortage. The ventricular assist device (VAD), as an important category of MCS, demonstrates promising applications in bridging heart transplantation, destination therapy, and bridge-to-decision. VADs can be categorized as durable VADs (dVADs) and temporary VADs (tVADs), according to the duration of assistance. With the technological advancement and clinical application experience accumulated, VADs have been developed in biocompatible, lightweight, bionic, and intelligent ways. In this review, we summarize the development history of VADs, focusing on the mechanism and application status of dVADs in detail, and further discuss the research progress and use of VADs in China.

Keywords: complications; durable ventricular assist devices; heart failure; mechanical circulatory support.

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Conflict of interest statement

The authors declare no conflicts of interest.

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References

    1. Tsao C.W., Aday A.W., Almarzooq Z.I., Anderson C., Arora P., Avery C.L., Baker-Smith C.M., Beaton A.Z., Boehme A.K., Buxton A.E., et al. Heart disease and stroke statistics-2023 update: A report from the american heart association. Circulation. 2023;147:e93–e621. - PubMed
    1. Yancy C.W., Jessup M., Bozkurt B., Butler J., Casey D.J., Drazner M.H., Fonarow G.C., Geraci S.A., Horwich T., Januzzi J.L., et al. 2013 ACCF/AHA guideline for the management of heart failure: A report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J. Am. Coll. Cardiol. 2013;62:e147–e239. doi: 10.1016/j.jacc.2013.05.019. - DOI - PubMed
    1. Ambrosy A.P., Fonarow G.C., Butler J., Chioncel O., Greene S.J., Vaduganathan M., Nodari S., Lam C., Sato N., Shah A.N., et al. The global health and economic burden of hospitalizations for heart failure: Lessons learned from hospitalized heart failure registries. J. Am. Coll. Cardiol. 2014;63:1123–1133. - PubMed
    1. Ma L.Y., Chen W.W., Gao R.L., Liu L.S., Zhu M.L., Wang Y.J., Wu Z.S., Li H.J., Gu D.F., Yang Y.J., et al. China cardiovascular diseases report 2018: An updated summary. J. Geriatr. Cardiol. 2020;17:1–8. - PMC - PubMed
    1. Mclarty A. Mechanical circulatory support and the role of LVADs in heart failure therapy. Clin. Med. Insights. Cardiol. 2015;9:CMC-S19694. - PMC - PubMed

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