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Review
. 2024 Jan 17;16(2):0.
doi: 10.3390/cancers16020393.

The Impact of Nanomedicine on Soft Tissue Sarcoma Treated by Radiotherapy and/or Hyperthermia: A Review

Maria-Eleni Zachou  1 , Vassilis Kouloulias  1 , Marina Chalkia  1 , Efstathios Efstathopoulos  1 , Kalliopi Platoni  1
Affiliations
Review

The Impact of Nanomedicine on Soft Tissue Sarcoma Treated by Radiotherapy and/or Hyperthermia: A Review

Maria-Eleni Zachou et al. Cancers (Basel). .

Abstract

This article presents a comprehensive review of nanoparticle-assisted treatment approaches for soft tissue sarcoma (STS). STS, a heterogeneous group of mesenchymal-origin tumors with aggressive behavior and low overall survival rates, necessitates the exploration of innovative therapeutic interventions. In contrast to conventional treatments like surgery, radiotherapy (RT), hyperthermia (HT), and chemotherapy, nanomedicine offers promising advancements in STS management. This review focuses on recent research in nanoparticle applications, including their role in enhancing RT and HT efficacy through improved drug delivery systems, novel radiosensitizers, and imaging agents. Reviewing the current state of nanoparticle-assisted therapies, this paper sheds light on their potential to revolutionize soft tissue sarcoma treatment and improve patient therapy outcomes.

Keywords: hyperthermia; nanoparticles; radiotherapy; soft tissue sarcoma.

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Conflict of interest statement

The authors declare no conflict of interest.

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