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Case Reports
. 2023 Dec 27;14(1):44.
doi: 10.3390/life14010044.

Large Lung Consolidation: A Rare Presentation of Pulmonary Sarcoidosis

Monica Steluta Marc  1   2 , Camelia Corina Pescaru  1   2 , Emanuela Oana Costin  2   3 , Alexandru Florian Crisan  2   4 , Adelina Maritescu  2   5 , Andrei Pescaru  6 , Noemi Suppini  1   2   5 , Gheorghe Emilian Olteanu  1   7   8 , Daniel Traila  1   2 , Cristian Oancea  1   2 , Diana Manolescu  2   9
Affiliations
Case Reports

Large Lung Consolidation: A Rare Presentation of Pulmonary Sarcoidosis

Monica Steluta Marc et al. Life (Basel). .

Abstract

Sarcoidosis is a complex inflammatory disease of uncertain origin, characterized by non-necrotizing epithelioid cell granulomas (NNEGs) affecting multiple organ systems. Although many different clinical and pathological phenotypes can be present, with different organs involved, the lung is the most common site described. In this case report, we (a) present and discuss the broad differential diagnosis of a patient presenting with a solitary lung mass with clinical and imaging features of lung cancer that ultimately was confirmed with a rare manifestation of stage II pulmonary sarcoidosis, and (b) analyze and compare similar cases from the literature.

Keywords: diagnosis; pulmonary sarcoidosis; treatment.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
CT scan at the baseline. Axial lung windows at the level of the middle lobe (a) and lower lobes (b) with a dense mass in the right middle lobe (RML), cuffing of bronchovascular bundle with perilymphatic micronodules. (c) Right paratracheal (4R) lymphadenopathy (arrow).
Figure 1
Figure 1
CT scan at the baseline. Axial lung windows at the level of the middle lobe (a) and lower lobes (b) with a dense mass in the right middle lobe (RML), cuffing of bronchovascular bundle with perilymphatic micronodules. (c) Right paratracheal (4R) lymphadenopathy (arrow).
Figure 2
Figure 2
Histopathology of the bronchial biopsy specimen (a) ×40 HE, (b) ×100 HE, (c) ×200, (d) and ×400. Nodular lesions along the bronchial wall (polypoid-like appearance) with non-necrotizing epithelioid granulomas with inflammatory lymphoplasmacytic infiltrate. Langhans-type multinucleated giant cell with Schaumann body. HE-hematoxylin and eosin.
Figure 3
Figure 3
CT scan after treatment. Axial lung windows at the level of the middle lobe (a) and lower lobes (b) show a decrease in the RML mass and some scars in the lower lobes. (c) Right paratracheal (4R) lymphadenopathy involution (arrow).
Figure 3
Figure 3
CT scan after treatment. Axial lung windows at the level of the middle lobe (a) and lower lobes (b) show a decrease in the RML mass and some scars in the lower lobes. (c) Right paratracheal (4R) lymphadenopathy involution (arrow).
See this image and copyright information in PMC

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