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. 2024 Jan 12;13(2):423.
doi: 10.3390/jcm13020423.

Early and Late Readmissions of Radiation Proctitis in the United States: Are We Getting Better?

Dushyant Singh Dahiya  1 , Bhanu Siva Mohan Pinnam  2 , Michelle Ishaya  2 , Saurabh Chandan  3 , Manesh Kumar Gangwani  4 , Sahib Singh  5 , Hassam Ali  6 , Amir Humza Sohail  7 , Andrew Canakis  8 , Daryl Ramai  9 , Christina Zelt  10 , Sumant Inamdar  11 , Mohammad Al-Haddad  12 , Mariajose Rojas-DeLeon  13 , Neil R Sharma  10
Affiliations

Early and Late Readmissions of Radiation Proctitis in the United States: Are We Getting Better?

Dushyant Singh Dahiya et al. J Clin Med. .

Abstract

Background/Aims: Radiation proctitis (RP), a well-known complication of pelvic radiation therapy, may lead to recurrent hospitalizations. We aimed to assess readmissions of RP in the United States. Methods: We analyzed the Nationwide Readmission Database from 2016 to 2020 to identify all 30-, 60-, and 90-day readmissions of RP in the United States. Hospitalization characteristics, predictors, clinical outcomes, and healthcare burdens were assessed. Results: From 2016 to 2020, we noted a declining trend of 30-, 60-, and 90-day readmissions of RP in the US. However, the all-cause 30-, 60-, and 90-day readmission rates of RP were still high at 13.7%, 19.4%, and 23.16%, respectively. On readmission, RP was identified as the admitting diagnosis in only 20.61%, 17.87%, and 15.76% of 30-, 60-, and 90-day readmissions, respectively. The mean age for all readmissions was 70 years with a significant male dominance. Lower endoscopy at index admission reduced the risk of readmissions within 90 days, but this was not statistically significant. However, the Charlson Comorbidity Index (CCI) score was an independent predictor of all readmissions. Furthermore, the mean length of stay was 5.57 (95% CI 5.15-6), 5.50 (95% CI 5.12-5.89), and 5.47 (95% CI 5.07-5.87) days and the mean hospitalization charge was USD 60,451 (95% CI USD 54,728-66,174), USD 62,671 (95% CI USD 57,326-68,015), and USD 62,144 (95% CI USD 57,144-67,144) for 30-, 60-, and 90-day readmissions. The all-cause inpatient mortality for 30-, 60-, and 90-day readmissions was 3.58%, 3.89%, and 3.46%, respectively. Conclusions: RP readmissions are a significant healthcare burden. Further efforts must be directed toward improving management strategies to reduce readmission rates.

Keywords: cost; mortality; outcomes; radiation proctitis; readmission.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
Yearly trends for 30-day, 60-day, and 90-day readmissions of radiation proctitis in the United States.
Figure 2
Figure 2
Kaplan–Meier curve for 90-day readmission for radiation proctitis stratified by colonoscopy at index admission.
See this image and copyright information in PMC

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References

    1. Culp M.B., Soerjomataram I., Efstathiou J.A., Bray F., Jemal A. Recent Global Patterns in Prostate Cancer Incidence and Mortality Rates. Eur. Urol. 2020;77:38–52. doi: 10.1016/j.eururo.2019.08.005. - DOI - PubMed
    1. Lin S., Gao K., Gu S., You L., Qian S., Tang M., Wang J., Chen K., Jin M. Worldwide trends in cervical cancer incidence and mortality, with predictions for the next 15 years. Cancer. 2021;127:4030–4039. doi: 10.1002/cncr.33795. - DOI - PubMed
    1. Gilinsky N.H., Burns D.G., Barbezat G.O., Levin W., Myers H.S., Marks I.N. The natural history of radiation-induced proctosigmoiditis: An analysis of 88 patients. QJM Int. J. Med. 1983;52:40–53. - PubMed
    1. Palmer J.A., Bush R.S. Radiation injuries to the bowel associated with the treatment of carcinoma of the cervix. Surgery. 1976;80:458–464. - PubMed
    1. NRD Overview 2023. [(accessed on 1 November 2023)]; Available online: https://www.hcup-us.ahrq.gov/nrdoverview.jsp.

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