Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1986 Nov;19(3-4):169-73.
doi: 10.1007/BF01966202.

3H-tiotidine binding to guinea-pig cortical and striatal membranes

I R Smith, B K Leigh, M E Mylek

3H-tiotidine binding to guinea-pig cortical and striatal membranes

I R Smith et al. Agents Actions. 1986 Nov.

Abstract

3H-Tiotidine has been identified as a suitable radioligand for the H2-receptor. We have confirmed and extended structure-binding affinity studies in the guinea-pig cortex, and established a structure-binding affinity relationship consistent with the H2-receptor in guinea-pig striatum. Cimetidine-displaceable 3H-tiotidine binding was observed also in the nucleus accumbens.

PubMed Disclaimer

References

    1. Nature. 1976 Mar 11;260(5547):163-5 - PubMed
    1. Life Sci. 1983 Sep 19;33(12):1119-26 - PubMed
    1. Agents Actions. 1984 Apr;14(3-4):543-5 - PubMed
    1. Proc Natl Acad Sci U S A. 1977 Dec;74(12):5697-701 - PubMed
    1. Am J Physiol. 1978 Aug;235(2):E97-102 - PubMed