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Case Reports
. 2024 Jan 22;10(1):513.
doi: 10.37029/jcas.v10i1.513. eCollection 2024.

A Rare Case of Primary Malignant Melanoma of Cervical Spine Having Extramedullary Intradural Origin: A Single Case Report and Literature Review

Irfan Haider  1 , Sarah Khan  2 , Fawad Ul Qamar  1 , Yasir Inam  1 , Kashmala Gul  1 , Iftikhar Ali Rana  3
Affiliations
Case Reports

A Rare Case of Primary Malignant Melanoma of Cervical Spine Having Extramedullary Intradural Origin: A Single Case Report and Literature Review

Irfan Haider et al. J Cancer Allied Spec. .

Abstract

Introduction: Primary spinal malignant melanoma (PSMM) of extramedullary intradural origin is a rare malignant condition with limited current literature regarding its clinical course, magnetic resonance imaging (MRI) findings, treatment strategies, and outcomes.

Case discussion: This is a case report of a patient with PSMM who was treated with surgery followed by radiotherapy for his residual disease in Shaukat Khanum Memorial Trust, Pakistan. The clinical and radiological findings of this case were retrospectively analyzed using the Hospital Information System.

Practical implementations: PSMM of extramedullary intradural origin is a rare malignant tumor that shows characteristic findings on MRI. Surgical resection is the preferred treatment, and radiotherapy is useful for residual disease.

Keywords: Cervical spine; extramedullary; intradural; malignant melanoma.

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Conflict of interest statement

Nil.

Figures

Figure 1
Figure 1
(a) Photomicrograph shows oval to spindle-shaped tumor cells with hyperchromatic nuclei. A few areas of melanin pigmentation are also visible. (H&E, ×200). (b-d) Positive immunoreactivity for S100 protein (×200), HMB-45 (×200), and Melan-A (×200)
Figure 2
Figure 2
(a) is the sagittal view of the magnetic resonance imaging (MRI) scan of the cervical spine, while (b) is the axial view of the same. Both images display a small 8-mm area of signal void in the cervical canal, located posteriorly and almost at the midline of the C3 level (indicated by a white arrow). (c and d) show the pre- and post-radiotherapy MRI scans of the cervical spine in sagittal view
See this image and copyright information in PMC

References

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