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Review
. 2024 Jan 8:17:1274432.
doi: 10.3389/fnins.2023.1274432. eCollection 2023.

Current status and prospect of transcutaneous auricular vagus nerve stimulation for disorders of consciousness

Yifei Wang  1 , Jinling Zhang  1 , Weihang Zhai  1 , Yu Wang  1 , Shaoyuan Li  1 , Yi Yang  2 , Yanfeng Zheng  1 , Jianghong He  2 , Peijing Rong  1
Affiliations
Review

Current status and prospect of transcutaneous auricular vagus nerve stimulation for disorders of consciousness

Yifei Wang et al. Front Neurosci. .

Abstract

Disordered Consciousness (DOC) is among neurological disorders for which there is currently no admitted treatment. The pathogenesis of DOC is still unclear, covering a variety of indistinguishable types of diseases, high misdiagnosis rate and poor prognosis. Most treatments remain to be clarified in the future to provide adequate evidence for clinical guidance. Neuromodulation technology aims to regulate neural circuits to promote awakening more directly. At present, it is confirmed that the potential of transcutaneous auricular vagus nerve stimulation (taVNS) as a therapeutic tool is worth exploring in the context of consciousness disorders, as previously proposed for invasive forms of VNS, in which the means of stimulating the vagus nerve to change the brain areas related to cosciousness have also received widespread attention. In this paper, we review the literature on taVNS and DOC to better understand the current status and development prospect of taVNS treament as a non-invasive neuromodulation method with sensitivity and/or specificity at the single subject.

Keywords: disorders of consciousness; neuromodulation; transcutaneous auricular vagus nerve stimulation; treament; vagus nerve.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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