Occupational allergic contact dermatitis from 2-butyl-1,2-benzisothiazol-3-one in cutting fluids: A case series

doi:10.1111/cod.14503

Case Reports

. 2024 May;90(5):520-522.

doi: 10.1111/cod.14503. Epub 2024 Jan 23.

Occupational allergic contact dermatitis from 2-butyl-1,2-benzisothiazol-3-one in cutting fluids: A case series

Lara Obermeyer^{1

2}, Katja Dicke^{1

2}, Christoph Skudlik^{1

2}, Richard Brans^{1

2}

Affiliations

¹ Institute for Interdisciplinary Dermatologic Prevention and Rehabilitation (iDerm), Osnabrück University, Osnabrück, Germany.
² Department of Dermatology, Environmental Medicine and Health Theory, Osnabrück University, Osnabrück, Germany.

PMID: 38263711
DOI: 10.1111/cod.14503

Case Reports

Occupational allergic contact dermatitis from 2-butyl-1,2-benzisothiazol-3-one in cutting fluids: A case series

Lara Obermeyer et al. Contact Dermatitis. 2024 May.

. 2024 May;90(5):520-522.

doi: 10.1111/cod.14503. Epub 2024 Jan 23.

Authors

Lara Obermeyer^{1

2}, Katja Dicke^{1

2}, Christoph Skudlik^{1

2}, Richard Brans^{1

2}

Affiliations

¹ Institute for Interdisciplinary Dermatologic Prevention and Rehabilitation (iDerm), Osnabrück University, Osnabrück, Germany.
² Department of Dermatology, Environmental Medicine and Health Theory, Osnabrück University, Osnabrück, Germany.

PMID: 38263711
DOI: 10.1111/cod.14503

No abstract available

Keywords: 2‐butyl‐1,2‐benzisothiazolin‐3‐one; 2‐n‐butyl‐benzo[d]isothiazol‐3‐one; BBIT; CAS no. 4299‐07‐4; contact dermatitis; isothiazolinone; metalworking fluid; occupational.

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Recent Advances in the Synthesis of Benzo[d]isothiazol-3(2H)-One and Benzo[e][1,3]Thiazin-4-One Derivatives.
He Y, Yuan D, Yang K, Li B. He Y, et al. Molecules. 2025 May 9;30(10):2099. doi: 10.3390/molecules30102099. Molecules. 2025. PMID: 40430272 Free PMC article. Review.

References

REFERENCES

1. Dahlin J, Isaksson M. Occupational contact dermatitis caused by N‐butyl‐1,2‐benzisothiazolin‐3‐one in a cutting fluid. Contact Dermatitis. 2015;73(1):60‐62. doi:10.1111/cod.12391
1. Jacobs MC, Herman A. Contact dermatitis from 2‐butyl‐1,2‐benzisothiazolin‐3‐one in a cutting fluid. Contact Dermatitis. 2020;83(5):414‐415. doi:10.1111/cod.13624
1. Foti C, Romita P, Stufano A, et al. Occupational allergic contact dermatitis caused by 2‐butyl‐1,2‐benzisothiazol‐3(2H)‐one in a metalworker. Contact Dermatitis. 2019;81(6):463‐465. doi:10.1111/cod.13366
1. Mahler V, Nast A, Bauer A, et al. S3 guidelines: Epicutaneous patch testing with contact allergens and drugs—short version, part 1. J Dtsch Dermatol Ges. 2019;17(10):1076‐1093. doi:10.1111/ddg.13956
1. Mahler V, Nast A, Bauer A, et al. S3 guidelines: Epicutaneous patch testing with contact allergens and drugs—short version, part 2. J Dtsch Dermatol Ges. 2019;17(11):1187‐1207. doi:10.1111/ddg.13971

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[1] Dahlin J, Isaksson M. Occupational contact dermatitis caused by N‐butyl‐1,2‐benzisothiazolin‐3‐one in a cutting fluid. Contact Dermatitis. 2015;73(1):60‐62. doi:10.1111/cod.12391

[2] Dahlin J, Isaksson M. Occupational contact dermatitis caused by N‐butyl‐1,2‐benzisothiazolin‐3‐one in a cutting fluid. Contact Dermatitis. 2015;73(1):60‐62. doi:10.1111/cod.12391

[3] Jacobs MC, Herman A. Contact dermatitis from 2‐butyl‐1,2‐benzisothiazolin‐3‐one in a cutting fluid. Contact Dermatitis. 2020;83(5):414‐415. doi:10.1111/cod.13624

[4] Jacobs MC, Herman A. Contact dermatitis from 2‐butyl‐1,2‐benzisothiazolin‐3‐one in a cutting fluid. Contact Dermatitis. 2020;83(5):414‐415. doi:10.1111/cod.13624

[5] Foti C, Romita P, Stufano A, et al. Occupational allergic contact dermatitis caused by 2‐butyl‐1,2‐benzisothiazol‐3(2H)‐one in a metalworker. Contact Dermatitis. 2019;81(6):463‐465. doi:10.1111/cod.13366

[6] Foti C, Romita P, Stufano A, et al. Occupational allergic contact dermatitis caused by 2‐butyl‐1,2‐benzisothiazol‐3(2H)‐one in a metalworker. Contact Dermatitis. 2019;81(6):463‐465. doi:10.1111/cod.13366

[7] Mahler V, Nast A, Bauer A, et al. S3 guidelines: Epicutaneous patch testing with contact allergens and drugs—short version, part 1. J Dtsch Dermatol Ges. 2019;17(10):1076‐1093. doi:10.1111/ddg.13956

[8] Mahler V, Nast A, Bauer A, et al. S3 guidelines: Epicutaneous patch testing with contact allergens and drugs—short version, part 1. J Dtsch Dermatol Ges. 2019;17(10):1076‐1093. doi:10.1111/ddg.13956

[9] Mahler V, Nast A, Bauer A, et al. S3 guidelines: Epicutaneous patch testing with contact allergens and drugs—short version, part 2. J Dtsch Dermatol Ges. 2019;17(11):1187‐1207. doi:10.1111/ddg.13971

[10] Mahler V, Nast A, Bauer A, et al. S3 guidelines: Epicutaneous patch testing with contact allergens and drugs—short version, part 2. J Dtsch Dermatol Ges. 2019;17(11):1187‐1207. doi:10.1111/ddg.13971

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Occupational allergic contact dermatitis from 2-butyl-1,2-benzisothiazol-3-one in cutting fluids: A case series

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Occupational allergic contact dermatitis from 2-butyl-1,2-benzisothiazol-3-one in cutting fluids: A case series

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