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. 2024 Feb;45(1):71-82.
doi: 10.1007/s00292-023-01294-2. Epub 2024 Jan 24.

[Fundamentals in the pathology of testicular tumours]

[Article in German]
Alexander Fichtner  1 , Felix Bremmer  2
Affiliations

[Fundamentals in the pathology of testicular tumours]

[Article in German]
Alexander Fichtner et al. Pathologie (Heidelb). 2024 Feb.

Abstract
in English, German

The most common group of testicular tumours comprises germ cell tumours. Other primary testicular tumours are rare, but it is important to be aware of the wide variety of other, much rarer testicular tumours for the differential diagnosis. These tumours include sex cord stromal tumours and testicular adnexal tumours, which must be distinguished from metastases or somatic-type malignancies in germ cell tumours. Immunohistochemical markers and molecular alterations can help to correctly diagnose these tumours.

Die Keimzelltumoren bilden die am häufigsten vorkommende Gruppe an primären Hodentumoren. Dennoch ist es wichtig, die große Vielfalt der anderen, deutlich selteneren Tumoren des Hodens in der differenzialdiagnostischen Betrachtung zu kennen. Zu diesen Tumoren zählen die Keimstrangstromatumoren und die testikulären Adnextumoren. Abzugrenzen sind diese Tumoren v. a. von Metastasen oder somatischen Malignitäten von Keimzelltumoren. Für die Diagnose dieser Hodentumoren können verschiedene immunhistochemische Marker und molekulare Veränderungen zu Hilfe gezogen werden.

Keywords: Mesothelial neoplasms; Ovarian-type tumours of the testis; Sex cord stromal tumors; Testicular adnexal tumours; Testis.

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