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. 2024 May;24(5):711-715.
doi: 10.1016/j.ajt.2024.01.023. Epub 2024 Jan 22.

Electronic health record-enabled routine assessment of medication adherence after solid organ transplantation: the time is now

Abbie D Leino  1 , Tiffany E Kaiser  2 , Karen Khalil  3 , Holly Mansell  4 , David J Taber  5
Affiliations

Electronic health record-enabled routine assessment of medication adherence after solid organ transplantation: the time is now

Abbie D Leino et al. Am J Transplant. 2024 May.

Abstract

Medication nonadherence after solid organ transplantation is recognized as an important impediment to long-term graft survival. Yet, assessment of adherence is often not part of routine care. In this Personal Viewpoint, we call for the transplant community to consider implementing a systematic process to screen and assess medication adherence. We believe acceptable tools are available to support integrating adherence assessments into the electronic health record. Creating a standard assessment can be done efficiently and cost-effectively if we come together as a community. More importantly, such monitoring can improve outcomes and strengthen provider-patient relationships. We further discuss the practical challenges and potential rebuttals to our position.

Keywords: adherence; electronic health record; maintenance immunosuppression.

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Conflict of interest statement

Declaration of competing interest The authors of this manuscript have no conflicts of interest to disclose as described by the American Journal of Transplant-ation.

References

    1. Dew MA, DiMartini AF, De Vito Dabbs A, et al. Rates and risk factors for nonadherence to the medical regimen after adult solid organ transplantation. Transplantation. 2007;83(7):858–873. 10.1097/01.tp.0000258599.65257.a6. - DOI - PubMed
    1. Neuberger JM, Bechstein WO, Kuypers DRJ, et al. Practical recommendations for long-term management of modifiable risks in kidney and liver transplant recipients: a guidance report and clinical checklist by the Consensus on Managing Modifiable Risk in Transplantation (COMMIT) group. Transplantation. 2017;101(4S): S1–S56. 10.1097/TP.0000000000001651. suppl 2. - DOI - PubMed
    1. Patel SJ, Hofmeyer BA, Moore CA, et al. Medication nonadherence monitoring and management in adult kidney transplantation: a survey of practices and perceptions at US-based transplant programs. J Am Coll Clin Pharm. 2021;4(9):1100–1108. 10.1002/jac5.1477. - DOI
    1. Brar A, Babakhani A, Salifu MO, Jindal RM. Evaluation of non-adherence in patients undergoing dialysis and kidney transplantation: United States transplantation practice patterns survey. Transplant Proc. 2014;46(5):1340–1346. 10.1016/j.transproceed.2013.12.051. - DOI - PubMed
    1. De Geest S, Burkhalter H, Bogert L, et al. Describing the evolution of medication nonadherence from pretransplant until 3 years post-transplant and determining pretransplant medication nonadherence as risk factor for post-transplant nonadherence to immunosuppressives: the Swiss Transplant Cohort Study. Transpl Int. 2014;27(7):657–666. 10.1111/tri.12312. - DOI - PubMed

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