Evolutionary expansion, functional diversification, and transcript profiling of plant Glutathione Peroxidases

Abstract

Glutathione peroxidases (GPXs) play a crucial role in combating activated oxygen species and have been widely studied for their involvement in stress responses. In addition to their stress-related functions, GPXs exhibit diverse roles such as immunological response, and involvement in growth and development. These enzymes are found in both animals and plants, with multiple families identified in the evolutionarily diverse species. These families consist of conserved genes as well as unique members, highlighting the evolutionary diversification of GPX members. While animals have eight GPX families, plants possess five families. Notably, plant genomes undergo duplication and expansion events, leading to an increase in the number of GPX genes and the overall size of the GPX superfamily. This expansion suggests a wide range of functional roles for GPX. In this study, the evolutionary diversification, family expansion, and diverse functional roles of GPX enzymes have been investigated. Additionally, the expression profile of Arabidopsis and Oryza sativa GPX genes were analyzed in different developmental stages, tissues, and abiotic stress conditions. Further extensive research has been required to unravel the intricate interplay between GPX and other proteins, to gain the comprehensive mechanism governing the physiological and developmental roles of GPX.

Keywords: Development; Evolution; Family expansion; Glutathione peroxidase; Plant; Stress.