Has the time come to redefine Parkinson's disease?

Affiliations

¹ Radboud University Medical Centre, Donders Institute for Brain, Cognition and Behaviour, Department of Neurology, Center of Expertise for Parkinson and Movement Disorders, Nijmegen 6500, Netherlands.
² CHDI Management for the CHDI Foundation, Princeton NJ, USA.
³ Radboud University Medical Centre, Donders Institute for Brain, Cognition and Behaviour, Department of Neurology, Center of Expertise for Parkinson and Movement Disorders, Nijmegen 6500, Netherlands. Electronic address: bas.bloem@radboudumc.nl.

Comment

Sirwan K L Darweesh et al. Lancet Neurol. 2024 Feb.

. 2024 Feb;23(2):130-133.

doi: 10.1016/S1474-4422(23)00503-3.

¹ Radboud University Medical Centre, Donders Institute for Brain, Cognition and Behaviour, Department of Neurology, Center of Expertise for Parkinson and Movement Disorders, Nijmegen 6500, Netherlands.
² CHDI Management for the CHDI Foundation, Princeton NJ, USA.
³ Radboud University Medical Centre, Donders Institute for Brain, Cognition and Behaviour, Department of Neurology, Center of Expertise for Parkinson and Movement Disorders, Nijmegen 6500, Netherlands. Electronic address: bas.bloem@radboudumc.nl.

No abstract available

Conflict of interest statement

We declare no competing interests.

A biological definition of neuronal α-synuclein disease: towards an integrated staging system for research.
Simuni T, Chahine LM, Poston K, Brumm M, Buracchio T, Campbell M, Chowdhury S, Coffey C, Concha-Marambio L, Dam T, DiBiaso P, Foroud T, Frasier M, Gochanour C, Jennings D, Kieburtz K, Kopil CM, Merchant K, Mollenhauer B, Montine T, Nudelman K, Pagano G, Seibyl J, Sherer T, Singleton A, Stephenson D, Stern M, Soto C, Tanner CM, Tolosa E, Weintraub D, Xiao Y, Siderowf A, Dunn B, Marek K. Simuni T, et al. Lancet Neurol. 2024 Feb;23(2):178-190. doi: 10.1016/S1474-4422(23)00405-2. Lancet Neurol. 2024. PMID: 38267190 Review.