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. 2024 Jan 24;24(1):65.
doi: 10.1186/s12905-024-02908-4.

Risk factors for perioperative blood transfusion in patients undergoing total laparoscopic hysterectomy

Xianghua Cao  1 , Xueliang Liu  1 , Xingxing Zhang  1 , Kefang Zhang  1 , Chuan Chen  2 , Qinfeng Yang  3 , Jian Wang  3 , Xueping Li  4 , Ling Wei  5
Affiliations

Risk factors for perioperative blood transfusion in patients undergoing total laparoscopic hysterectomy

Xianghua Cao et al. BMC Womens Health. .

Abstract

Purpose: The goal is to identify risk factors associated with receiving a blood transfusion during the perioperative period in patients who undergo total laparoscopic hysterectomy (TLH) using a large-scale national database.

Methods: In this retrospective analysis, data from the Nationwide Inpatient Sample (NIS) was utilized to review the medical records of all patients who underwent TLH from 2010 to 2019. The researchers identified patients who had received a blood transfusion during the perioperative period and compared with those who had not. The subsequent factors associated with blood transfusion were examined: hospital characteristics (type of admission and payer, patient demographics (age and race), bed size, teaching status, location, and region of hospital), length of stay (LOS), total charges during hospitalization, in-hospital mortality, comorbidities, and perioperative complications. The data was analyzed using descriptive statistics. The independent risk factors of perioperative blood transfusion after TLH was identified by performing multivariate logistic regression.

Results: A total of 79,933 TLH were captured from the NIS database, among which 3433 (4.40%) patients received a perioperative blood transfusion. TLH patients affected by blood transfusion were 2 days longer hospital stays (P < 0.001), higher overall costs (P < 0.001), the patients who received a transfusion after a long-term hospitalization had a significantly higher rate of mortality (0.5% vs. 0.1%; P < 0.001). Perioperative blood transfusion after TLH was associated with chronic blood loss anemia, deficiency anemia, coagulopathy, congestive heart failure, fluid and electrolyte disorders, renal failure, metastatic cancer, sepsis, weight loss, deep vein thrombosis, gastrointestinal hemorrhage, shock, acute myocardial infarction, and pneumonia, stroke, hemorrhage, pulmonary embolism, and disease of the genitourinary system.

Conclusion: Studying the risk factors of perioperative blood transfusion after TLH is advantageous in order to ensure proper management and optimize outcomes.

Keywords: Blood transfusion; Nationwide inpatient sample; Risk factors; Total laparoscopic hysterectomy.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
Flow and inclusion/exclusion of all patients had TLH
Fig. 2
Fig. 2
Annual incidence of blood transfusion after TLH
Fig. 3
Fig. 3
Risk factors associated with blood transfusion after TLH
Fig. 4
Fig. 4
Comorbidities associated with blood transfusion following TLH
Fig. 5
Fig. 5
Complications associated with blood transfusion following TLH
See this image and copyright information in PMC

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