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Review
. 2024 Jan 22;16(2):322.
doi: 10.3390/nu16020322.

Gluten and Wheat in Women's Health: Beyond the Gut

Francesca Manza  1 , Lisa Lungaro  1 , Anna Costanzini  1 , Fabio Caputo  1 , Umberto Volta  2 , Roberto De Giorgio  1 , Giacomo Caio  1   3
Affiliations
Review

Gluten and Wheat in Women's Health: Beyond the Gut

Francesca Manza et al. Nutrients. .

Abstract

Since the rise of awareness of gluten/wheat-related disorders in the academic and clinical field in the last few decades, misinformation regarding the gluten-free diet (GFD) and its impact on health has been spreading among the general population. Despite the established link between gluten and celiac disease (CD), where a GFD is mandatory to reach clinical and histological remission, things are more complicated when it comes to non-celiac gluten/wheat sensitivity (NCGWS) and other autoimmune/dysimmune disorders. In the last conditions, a beneficial effect of gluten withdrawal has not been properly assessed, but still is often suggested without strong supporting evidence. In this context, women have always been exposed, more than men, to higher social pressure related to nutritional behaviors and greater engagement in controlling body weight. With this narrative review, we aim to summarize current evidence on the adherence to a GFD, with particular attention to the impact on women's health.

Keywords: autoimmune thyroiditis; autoimmunity; endometriosis; exclusion diet; fibromyalgia; gluten-free diet; irritable bowel syndrome; non-celiac gluten sensitivity; wheat; women.

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Conflict of interest statement

The authors declare no conflicts of interest.

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