Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2024 Jan;6(1):e230164.
doi: 10.1148/rycan.230164.

Carcinoid Heart Disease

Affiliations

Carcinoid Heart Disease

Sean Johnson et al. Radiol Imaging Cancer. 2024 Jan.
No abstract available

Keywords: Bioprosthetic Valve; Carcinoid; DOTATATE; Heart; Heart Disease; PET/CT.

PubMed Disclaimer

Conflict of interest statement

Disclosures of conflicts of interest: S.J. No relevant relationships. M.R.B. No relevant relationships. K.R. No relevant relationships.

Figures

A 45-year-old male patient with carcinoid heart disease. (A) Cardiac CT image
shows enlargement of the right atrium (*) and ventricle (o). (B) Coronal
tetraazacyclododecane tetraacetic acid–octreotate (DOTATATE) PET/CT image
shows the primary small bowel lesion (blue arrow) and multiple liver metastases
(white arrow) with high somatostatin receptor expression. When compared with
baseline study (C), there is mildly decreased but persistent high somatostatin
receptor expression in the majority of the liver metastases after four cycles of
lutetium 177-DOTATATE (Lutathera; Novartis) (D).
A 45-year-old male patient with carcinoid heart disease. (A) Cardiac CT image shows enlargement of the right atrium (*) and ventricle (o). (B) Coronal tetraazacyclododecane tetraacetic acid–octreotate (DOTATATE) PET/CT image shows the primary small bowel lesion (blue arrow) and multiple liver metastases (white arrow) with high somatostatin receptor expression. When compared with baseline study (C), there is mildly decreased but persistent high somatostatin receptor expression in the majority of the liver metastases after four cycles of lutetium 177-DOTATATE (Lutathera; Novartis) (D).

References

    1. Hassan SA , Palaskas NL , Agha AM , et al. . Carcinoid Heart Disease: a Comprehensive Review . Curr Cardiol Rep 2019. ; 21 ( 11 ): 140 . - PubMed
    1. Bhattacharyya S , Davar J , Dreyfus G , Caplin ME . Carcinoid heart disease . Circulation 2007. ; 116 ( 24 ): 2860 – 2865 . - PubMed
    1. Lundin L , Norheim I , Landelius J , Oberg K , Theodorsson-Norheim E . Carcinoid heart disease: relationship of circulating vasoactive substances to ultrasound-detectable cardiac abnormalities . Circulation 1988. ; 77 ( 2 ): 264 – 269 . - PubMed
    1. Davar J , Connolly HM , Caplin ME , et al. . Diagnosing and managing carcinoid heart disease in patients with neuroendocrine tumors: an expert statement . J Am Coll Cardiol 2017. ; 69 ( 10 ): 1288 – 1304 . - PubMed
    1. Hassan SA , Banchs J , Iliescu C , Dasari A , Lopez-Mattei J , Yusuf SW . Carcinoid heart disease . Heart 2017. ; 103 ( 19 ): 1488 – 1495 . - PubMed

MeSH terms

LinkOut - more resources