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Review
. 2024;24(5):416-436.
doi: 10.2174/0115680266276823231230183519.

P-coumaric Acid: Advances in Pharmacological Research Based on Oxidative Stress

Feixiang Chen  1 , Xinxin Zhang  1 , Junxiang Wang  2 , Fukai Wang  3 , Jinlong Mao  1
Affiliations
Review

P-coumaric Acid: Advances in Pharmacological Research Based on Oxidative Stress

Feixiang Chen et al. Curr Top Med Chem. 2024.

Abstract

P-coumaric acid is an important phenolic compound that is mainly found in fruits, vegetables, grains, and fungi and is also abundant in Chinese herbal medicines. In this review, the pharmacological research progress of p-coumaric acid in recent years was reviewed, with emphasis on its role and mechanism in oxidative stress-related diseases, such as inflammation, cardiovascular diseases, diabetes, and nervous system diseases. Studies have shown that p-coumaric acid has a positive effect on the prevention and treatment of these diseases by inhibiting oxidative stress. In addition, p-coumaric acid also has anti-tumor, antibacterial, anti-aging skin and other pharmacological effects. This review will provide reference and inspiration for further research on the pharmacological effects of p-coumaric acid.

Keywords: Anti-inflammation; Antioxidatives; Cardioprotective; Diabetes.; Neuroprotective; P-coumaric acid.

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