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Case Reports
. 2023 Oct 18:46:62.
doi: 10.11604/pamj.2023.46.62.41687. eCollection 2023.

Hashimoto's thyroiditis presenting with cardiac tamponade: a case report

Affiliations
Case Reports

Hashimoto's thyroiditis presenting with cardiac tamponade: a case report

Muhammadnur Rachim Enoch et al. Pan Afr Med J. .

Abstract

Cardiac tamponade as the initial manifestation of Hashimoto's thyroiditis is an exceedingly uncommon occurrence. We present the case of a 36-year-old female who was admitted due to acute respiratory distress. A cardiac ultrasound revealed a severe pericardial effusion with tamponade signs. Subsequently, percutaneous pericardiocentesis was performed, resulting in a swift clinical improvement. Laboratory examinations confirmed severe hypothyroidism associated with Hashimoto's disease. Despite undergoing hormone replacement therapy, histological analysis of the pericardium revealed a chronic inflammation process. A follow-up cardiac ultrasound conducted six months later indicated the presence of a well-tolerated chronic pericardial effusion. In conclusion, clinicians should consider hypothyroidism as a potential cause when cardiac tamponade is observed, particularly in the absence of tachycardia. The prognosis is generally favorable with hormone replacement therapy, but regular ultrasound monitoring should be maintained until the patient achieves a euthyroid state.

Keywords: Cardiac tamponade; Hashimoto’s thyroiditis; case report; hypothyroidism.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Figure 1
Figure 1
the ECG showing normal sinus rhythm with low voltage, right axis deviation (RAD), and incomplete right bundle branch block (RBBB)
Figure 2
Figure 2
chest radiogram showing cardiomegaly with globular enlargement of the cardiac silhouette with “water bottle” configuration
Figure 3
Figure 3
a two-dimensional transthoracic echocardiography reveals a significant pericardial effusion surrounding the heart; the red arrow indicates the effusion, while the blue arrow indicates right ventricular (RV) collapse; (LV: left ventricular, LA: left atrium, RA: right atrium)
Figure 4
Figure 4
the follow-up echocardiography after pericardiocentesis

References

    1. Udovcic M, Pena RH, Patham B, Tabatabai L, Kansara A. Hypothyroidism And The Heart. Meth Deb Car J. 2017 Apr-Jun;13(2):55–59. - PMC - PubMed
    1. Chiu MH, Sharma NC. A case of hypertensive emergency, primary hypothyroidism and large pericardial effusion with early tamponade. J Cardiol Cases. 2018 Apr 26;18(1):29–32. - PMC - PubMed
    1. Sinha A, Yeruva SLH, Kumar R, Curry BH. Early cardiac tamponade in a patient with postsurgical hypothyroidism. Case Rep Cardiol. 2015:310350. 2015. - PMC - PubMed
    1. Bajaj R, Mehrzad R, Singh K, Gupta JP. Cardiac tamponade in hypothyroidism. BMJ Case Rep. 2014 May 26;:bcr2014204076. 2014. - PMC - PubMed
    1. Baldwin C, Newman JD, Vallejo F, Peck V, Greene LW, Goldberg IJ. Myxedema heart and pseudotamponade. J Endocr Soc. 2020 Aug 27;5(1):bvaa125. - PMC - PubMed

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