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Case Reports
. 2023 Dec 27;15(12):e51200.
doi: 10.7759/cureus.51200. eCollection 2023 Dec.

Wilson's Disease in a 17-Year-Old Male With Sickle Cell Trait: A Report of a Rare Case

Aditya Jain  1 , Revat J Meshram  1 , Sham Lohiya  1 , Dinesh V Hinge  1 , Shailesh Wandile  1
Affiliations
Case Reports

Wilson's Disease in a 17-Year-Old Male With Sickle Cell Trait: A Report of a Rare Case

Aditya Jain et al. Cureus. .

Abstract

This case report describes the atypical presentation of Wilson's disease in a 17-year-old male with sickle cell trait AS pattern. The patient initially presented with fever, generalized weakness, and joint pain, leading to an inconclusive diagnosis and unsuccessful initial treatment. A comprehensive re-evaluation revealed vitamin-A deficiency, adenoid hypertrophy, splenomegaly, and acalculous cholecystitis. Elevated copper levels in the 24-hour urine test confirmed the diagnosis of Wilson's disease. Treatment was modified to include amikacin, prednisolone, and Zinconia®, with analgesics for joint pain management. This case emphasizes the need for a thorough diagnostic approach and consideration of overlapping conditions in complex presentations, contributing to improved patient outcomes.

Keywords: acalculous cholecystitis; adolescents; multidisciplinary approach; sickle cell trait; vitamin-a deficiency; wilson's disease.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. The figure shows yellowish discolouration of the eyes.
Figure 2
Figure 2. The figure shows pitting oedema over the lower limbs.
See this image and copyright information in PMC

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