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. 2024 Jan;35(1):e14082.
doi: 10.1111/pai.14082.

Surveillance for rubella virus in samples obtained from non-immunodeficient individuals

Affiliations

Surveillance for rubella virus in samples obtained from non-immunodeficient individuals

Srushti Patel et al. Pediatr Allergy Immunol. 2024 Jan.
No abstract available

Keywords: granuloma; immunodeficiencies; inborn errors of immunity; rubella.

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Conflict of interest statement

CONFLICT OF INTEREST STATEMENT

The authors declare no conflicts of interest for this work.

Figures

FIGURE 1
FIGURE 1
The fluorescent immunohistochemistry used to detect RuV in biopsy samples is displayed. (A) A representative negative result. (B) A representative positive result for comparison.

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References

    1. Bodemer C, Sauvage V, Mahlaoui N, et al. Live rubella virus vaccine long-term persistence as an antigenic trigger of cutaneous granulomas in patients with primary immunodeficiency. Clin Microbiol Infect. 2014;20(10):O656–O663. - PubMed
    1. Perelygina L, Plotkin S, Russo P, et al. Rubella persistence in epidermal keratinocytes and granuloma M2 macrophages in patients with primary immunodeficiencies. J Allergy Clin Immunol. 2016;138(5):1436–1439.e1411. - PMC - PubMed
    1. Perelygina L, Chen MH, Suppiah S, et al. Infectious vaccine-derived rubella viruses emerge, persist, and evolve in cutaneous granulomas of children with primary immunodeficiencies. PLoS Pathog. 2019;15(10):e1008080. - PMC - PubMed
    1. Kanbayashi D, Kurata T, Kaida A, et al. Shedding of rubella virus in postsymptomatic individuals; viral RNA load is a potential indicator to estimate candidate patients excreting infectious rubella virus. J Clin Virol. 2023;160:105377. - PubMed
    1. Perelygina L, Faisthalab R, Abernathy E, et al. Rubella virus infected macrophages and neutrophils define patterns of granulomatous inflammation in inborn and acquired errors of immunity. Front Immunol. 2021;12:796065. - PMC - PubMed

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