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Review

Illuminating Neural Computation Using Precision Optogenetics-Controlled Synthetic Perception

In: All-Optical Methods to Study Neuronal Function [Internet]. New York: Humana; 2023. Chapter 12.
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Review

Illuminating Neural Computation Using Precision Optogenetics-Controlled Synthetic Perception

Jonathan V. Gill et al.
Free Books & Documents

Excerpt

Connecting neuronal activity to perception requires tools that can probe neural codes at cellular and circuit levels, paired with sensitive behavioral measures. In this chapter, we present an overview of current methods for connecting neural codes to perception using precision optogenetics and psychophysical measurements of synthetically induced percepts. We also highlight new methodologies for validating precise control of optical and behavioral manipulations. Finally, we provide a perspective on upcoming developments that are poised to advance the field.

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References

    1. Kandel ER, Schwartz JH, Jessell TM (2000) Principles of neural science, vol 4. McGraw-Hill, New York
    1. Dayan P, Abbott LF (2001) Theoretical neuroscience: computational and mathematical modeling of neural systems, Computational Neuroscience Series. MIT Press
    1. Jun JJ et al (2017) Fully integrated silicon probes for high-density recording of neural activity. Nature 551:232 - PMC - PubMed
    1. Sofroniew NJ et al (2016) A large field of view two-photon mesoscope with subcellular resolution for in vivo imaging. elife 5:e14472 - PMC - PubMed
    1. Shusterman R et al (2011) Precise olfactory responses tile the sniff cycle. Nat Neurosci 14(8):1039–1044 - PubMed

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