Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2024 Jan 16:10:1332432.
doi: 10.3389/fmed.2023.1332432. eCollection 2023.

Critical importance of patient-reported outcomes for a comprehensive assessment of psoriatic arthritis patients

Marika Lo Monaco #  1   2 , Raffaella Mallaci Bocchio #  2 , Giuseppe Natoli #  2 , Annarita Giardina #  2 , Ignazio Cangemi #  2 , Salvatore Scibetta #  2 , Christiano Argano #  2 , Salvatore Corrao #  1   2
Affiliations

Critical importance of patient-reported outcomes for a comprehensive assessment of psoriatic arthritis patients

Marika Lo Monaco et al. Front Med (Lausanne). .

Abstract

Introduction: Psoriatic arthritis (PsA) is a heterogeneous, chronic inflammatory disease that negatively impacts patients' quality of life. Patient-reported outcome measures (PROMs) are used to capture patient perspectives in disease assessment, and physicians use the Disease Activity Index for Psoriatic Arthritis (DAPSA) to evaluate disease activity in PsA. The study aimed to assess the relationship between PROMs and the DAPSA score in consecutive outpatients affected by PsA.

Materials and methods: A cross-sectional study was conducted from March 2018 to October 2020 at the PsA clinic of the ARNAS Civico in Palermo (Italy), enrolling outpatients with PsA. Patients were assessed for their disease activity according to the DAPSA score, and PROMs, such as PHQ-9, HAQ, FACIT-F, and PsAID, were evaluated. Linear regression analysis evaluated the relationship between the DAPSA Score and the included PROMs.

Results: 158 PsA consecutive peripheral subset psoriatic arthritis outpatients were recruited. The median years of illness was 10.6 (9.3-11.9), and the median DAPSA score was 19.02 (9-33.1). The regression analysis highlighted a strong relationship between the DAPSA score and the PsAID (adjR2 26%, p < 0.0001), the FACIT-F (adjR2 25.4%, p < 0.0001), the HAQ (adjR2 23.7%, p < 0.0001), and PHQ-9 (adjR2 15%, p < 0.0001).

Conclusion: PROMs are strongly associated with the DAPSA score, but it allows in-depth evaluation of the impact of the disease on different domains of PsA patients' life.

Keywords: disease activity; multidimensional assessment; nurse assessment; nursing; patient reported outcomes; psoriatic disease; quality of life; rheumatology.

PubMed Disclaimer

Conflict of interest statement

The authors declare that the research was conducted without any commercial or financial relationships that could be construed as a potential conflict of interest. The author(s) declared that they were an editorial board member of Frontiers, at the time of submission. This had no impact on the peer review process and the final decision.

Figures

Figure 1
Figure 1
Linear relationships between DAPSA and PsAID.
Figure 2
Figure 2
Linear relationships between DAPSA and Facit-F.
Figure 3
Figure 3
Linear relationships between DAPSA and HAQ.
Figure 4
Figure 4
Linear relationships between DAPSA and PHQ-9.
See this image and copyright information in PMC

Similar articles

See all similar articles

References

    1. Ogdie A, Weiss P. The epidemiology of psoriatic arthritis. Rheum Dis Clin North Am. (2015) 41:545–68. doi: 10.1016/j.rdc.2015.07.001, PMID: - DOI - PMC - PubMed
    1. Karmacharya P, Chakradhar R, Ogdie A. The epidemiology of psoriatic arthritis: a literature review. Best Pract Res Clin Rheumatol. (2021) 35:101692. doi: 10.1016/j.berh.2021.101692 - DOI - PubMed
    1. Gialouri CG, Evangelatos G, Zhao SS, Kouna K, Karamanakos A, Iliopoulos A, et al. . Depression and anxiety in a real-world psoriatic arthritis longitudinal study: should we focus more on patients’ perception? Clin Exp Rheumatol. (2023) 41:159–65. doi: 10.55563/clinexprheumatol/8qxo80 - DOI - PubMed
    1. Taylor W, Gladman D, Helliwell P, Marchesoni A, Mease P, Mielants H, et al. . Classification criteria for psoriatic arthritis: development of new criteria from a large international study. Arthritis Rheum. (2006) 54:2665–73. doi: 10.1002/art.21972 - DOI - PubMed
    1. Aletaha D, Alasti F, Smolen JS. Disease activity states of the DAPSA, a psoriatic arthritis-specific instrument, are valid against functional status and structural progression. Ann Rheum Dis. (2017) 76:418–21. doi: 10.1136/annrheumdis-2016-209511, PMID: - DOI - PubMed