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. 2024 Apr 1;32(7):296-301.
doi: 10.5435/JAAOS-D-23-00957. Epub 2024 Jan 30.

American Academy of Orthopaedic Surgeons Technology Overview Summary: Platelet-Rich Plasma (PRP) for Knee Osteoarthritis

Jonathan Dubin  1 , Philipp Leucht, Martha Murray, Ryan Pezold; Staff of the American Academy of Orthopaedic Surgeons on Behalf of the Platelet-Rich Plasma (PRP) for Knee Osteoarthritis Technology Overview Workgroup and Contributors
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American Academy of Orthopaedic Surgeons Technology Overview Summary: Platelet-Rich Plasma (PRP) for Knee Osteoarthritis

Jonathan Dubin et al. J Am Acad Orthop Surg. .

Abstract

The Platelet-Rich Plasma (PRP) for Knee Osteoarthritis Technology Overview is based on a systematic review of current scientific and clinical research. Through analysis of the current best evidence, this technology overview seeks to evaluate the efficacy of PRP for patients with knee osteoarthritis. The systematic literature review resulted in 54 articles: 36 high-quality and 18 moderate-quality. The findings of these studies were summarized to present findings on PRP versus control/placebo, acetaminophen, non-steroidal anti-inflammatory drugs, corticosteroids, exercise, prolotherapy, autologous conditioned serum, bone marrow aspirate concentrate, hyaluronic acid, and ozone therapy. In addition, the work group highlighted areas that needed additional research when evidence proved lacking on the topic and carefully noted the potential harms associated with an intervention, required resource utilization, acceptability, and feasibility.

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References

    1. American Academy of Orthopaedic Surgeons Technology Overview for Platelet-Rich Plasma (PRP) for Knee Osteoarthritis. Accessed June 20, 2022 https://www.aaos.org/techoverviewprpknee
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    1. Buendia-Lopez D, Medina-Quiros M, Fernandez-Villacanas Marin MA: Clinical and radiographic comparison of a single LP-PRP injection, a single hyaluronic acid injection and daily NSAID administration with a 52-week follow-up: A randomized controlled trial. J OrthopTraumatol2018;19:3.

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