Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2024 Jan 20;40(1):90-95.
doi: 10.3760/cma.j.cn501225-20231026-00136.

[Research advances of collagen-based biomaterials in wound repair]

[Article in Chinese]
Affiliations
Review

[Research advances of collagen-based biomaterials in wound repair]

[Article in Chinese]
Z Q Dong et al. Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za Zhi. .

Abstract

Acute or chronic wounds are common clinical problems. Collagen, with advantages including rich sources, impeccable biocompatibility, and inherent biodegradability, has been widely used in fundamental research and clinical treatment of wound repair with broad prospects of clinical applications. This article provided a brief overview of the role of collagen in various biological processes related to wound healing and also outlined the sources of collagen. Furthermore, the article summarized the application and recent research advancements of collagen-based wound dressings in the field of wound repair.

急性或慢性创面是常见的临床问题。胶原蛋白因具有来源丰富、生物相容性良好、免疫原性低以及可生物降解等诸多优点,被广泛用于创面修复的基础研究和临床治疗,具有广阔的临床应用前景。该文简要回顾胶原蛋白在创面愈合相关的不同生物学过程中的作用,对胶原蛋白的来源进行了概述;此外,该文还总结了基于胶原蛋白的创面敷料在创面修复领域中的应用情况及最新研究进展。.

PubMed Disclaimer

Conflict of interest statement

利益冲突 所有作者均声明不存在利益冲突

References

    1. Gao Y, Sun W, Zhang Y, et al. All-aqueous microfluidics fabrication of multifunctional bioactive microcapsules promotes wound healing. ACS Appl Mater Interfaces. 2022;14(43):48426–48437. doi: 10.1021/acsami.2c13420. - DOI - PubMed
    1. Adamiak K, Sionkowska A. Current methods of collagen cross-linking: review. Int J Biol Macromol. 2020;161:550–560. doi: 10.1016/j.ijbiomac.2020.06.075. - DOI - PubMed
    1. 刘 小刚, 陈 蕾, 李 海航, et al. 天然与重组胶原蛋白在创面修复中的应用研究进展. 中华烧伤与创面修复杂志. 2022;38(10):978–982. doi: 10.3760/cma.j.cn501120-20211123-00394. - DOI - PMC - PubMed
    1. Wang Y, Zhang Y, Li T, et al. Adipose mesenchymal stem cell derived exosomes promote keratinocytes and fibroblasts embedded in collagen/platelet-rich plasma scaffold and accelerate wound healing. Adv Mater. 2023;35(40):e2303642. doi: 10.1002/adma.202303642. - DOI - PubMed
    1. Davison-Kotler E, Marshall WS, García-Gareta E. Sources of collagen for biomaterials in skin wound healing. Bioengineering (Basel) 2019;6(3):56. doi: 10.3390/bioengineering6030056. - DOI - PMC - PubMed

MeSH terms

LinkOut - more resources