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Review
. 1978:(13):81-95.

Studies on the control of pineal indole synthesis: cyclic nucleotides, adenylate cyclase and phosphodiesterase

  • PMID: 38299
Review

Studies on the control of pineal indole synthesis: cyclic nucleotides, adenylate cyclase and phosphodiesterase

M A Oleshansky et al. J Neural Transm Suppl. 1978.

Abstract

An overview of the biochemical events that occur when postsynaptic pineal beta-adrenergic receptors are stimulated is presented. Emphasis is placed on the importance of the adenylate cyclase system for the induction of N-acetyltransferase (NAT). Super- and subsensitive responses of NAT to receptor agonists are related to cAMP concentration, adenylate cyclase and phosphodiesterase activities and receptor binding sites.

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