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. 2024 Mar 12;13(3):e0123123.
doi: 10.1128/mra.01231-23. Epub 2024 Feb 1.

Complete reference genomes of two ceftriaxone-resistant Neisseria gonorrhoeae strains identified in routine surveillance in Bangkok, Thailand, using Nanopore Q20+ chemistry, VolTRAX V2b, and Illumina sequencing

Pongsathorn Sangprasert #  1 , Daniel Golparian #  2 , Porntip Paopang  1 , Natnaree Girdthep  1 , Ratana Lawung  3 , Deyer Gopinath  4 , Panithee Thammawijaya  5 , Rossaphorn Kittiyaowanarn #  1 , Magnus Unemo #  2   6
Affiliations

Complete reference genomes of two ceftriaxone-resistant Neisseria gonorrhoeae strains identified in routine surveillance in Bangkok, Thailand, using Nanopore Q20+ chemistry, VolTRAX V2b, and Illumina sequencing

Pongsathorn Sangprasert et al. Microbiol Resour Announc. .

Abstract

Ceftriaxone-resistant Neisseria gonorrhoeae strains, mostly associated with Asia, threaten gonorrhea treatment. We report the reference genomes of two ceftriaxone-resistant isolates found in routine surveillance in Bangkok, Thailand. The genomes belonged to the more antimicrobial-susceptible genomic lineage B, illustrating that both ceftriaxone-resistant strains and the mosaic penA-60.001 ceftriaxone-resistance determinant are spreading.

Keywords: Neisseria gonorrhoeae; Thailand; ceftriaxone resistance.

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Conflict of interest statement

The authors declare no conflict of interest.

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