Lessons Are Still Being Learned about Intrapulmonary Antibiotic Concentrations
- PMID: 38300143
- PMCID: PMC10995571
- DOI: 10.1164/rccm.202312-2338ED
Lessons Are Still Being Learned about Intrapulmonary Antibiotic Concentrations
Comment on
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Antimicrobial Drug Penetration Is Enhanced by Lung Tissue Inflammation and Injury.Am J Respir Crit Care Med. 2024 Apr 1;209(7):829-839. doi: 10.1164/rccm.202306-0974OC. Am J Respir Crit Care Med. 2024. PMID: 38099833
References
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- Ambrose PG, Bhavnani SM, Ellis-Grosse EJ, Drusano GL. Pharmacokinetic-pharmacodynamic considerations in the design of hospital-acquired or ventilator-associated bacterial pneumonia studies: look before you leap! Clin Infect Dis . 2010;51(Suppl 1):S103–S110. - PubMed
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- Rodvold KA, Hope WW, Boyd SE. Considerations for effect site pharmacokinetics to estimate drug exposure: concentrations of antibiotics in the lung. Curr Opin Pharmacol . 2017;36:114–123. - PubMed
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