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Case Reports
. 2024 Jan 2;16(1):e51528.
doi: 10.7759/cureus.51528. eCollection 2024 Jan.

Hypofractionated Radiotherapy as a Standalone Treatment Modality for Locally Advanced Type B2 Thymoma in an Octogenarian Patient: 45 Gy in 15 Fractions

Atsuto Katano  1 , Yuki Kasuga  1 , Shingo Ohira  2 , Masanari Minamitani  2 , Hideomi Yamashita  1
Affiliations
Case Reports

Hypofractionated Radiotherapy as a Standalone Treatment Modality for Locally Advanced Type B2 Thymoma in an Octogenarian Patient: 45 Gy in 15 Fractions

Atsuto Katano et al. Cureus. .

Abstract

Thymic epithelial tumors (TETs), particularly type B2 thymomas, are rare neoplasms primarily found in the anterior mediastinum. The current therapeutic approach includes surgery, chemotherapy, and radiotherapy, but there is limited research on radiotherapy as a standalone treatment. This case report aims to elucidate the clinical outcomes of hypofractionated radiotherapy as a standalone treatment for locally advanced type B2 thymoma, offering insights into its potential efficacy and role in clinical practice.

Keywords: definitive treatment; hypofractionation; octogenarian; radiotherapy; thymoma.

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Conflict of interest statement

Masanari Minamitani, and Shingo Ohira are affiliated with the Department of Comprehensive Radiation Oncology, which is an endowed department funded by an unrestricted grant from Elekta K.K. and Chiyoda Technol Corporation. However, it is important to note that no funding was received from them specifically to conduct this study.

Figures

Figure 1
Figure 1. PET/CT scan
A positron emission tomography/computed tomography (PET/CT) scan showed increased uptake in the anterior mediastinal lesion with a maximum standardized uptake value of 7.4.
Figure 2
Figure 2. Dose distributions
Dose distributions in the axial (upper), sagittal (lower left), and coronal (lower right) views for the radiotherapy plans
Figure 3
Figure 3. Chest CT scan
Chest computed tomography (CT) scan before the radiotherapy (A), three months after (B), 16 months after radiotherapy (C), and 28 months after radiotherapy (D). Yellow arrows indicate the target lesion.
See this image and copyright information in PMC

References

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