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Case Reports
. 2024 Jan 15;186(3):V07230476.
doi: 10.61409/V07230476.

Mesothelioma of the tunica vaginalis testis

[Article in Danish]
Katia Damsgaard Højsager  1 , Hanne Kobberø  1 , Eric Santoni-Rugiu  2 , Lotte Holm Land  3 , Jens Benn Sørensen  4
Affiliations
Free article
Case Reports

Mesothelioma of the tunica vaginalis testis

[Article in Danish]
Katia Damsgaard Højsager et al. Ugeskr Laeger. .
Free article

Abstract

Mesothelioma of the tunica vaginalis testis (MTVT) is a rare tumour and a cause of hydrocele. This case report concerns a 26-year-old male with hydrocele treated with left hydrocelectomy. Histopathology revealed MTVT, and left radical orchiectomy was performed followed by chemotherapy. Fluorescence in situ hybridization, DNA and RNA next-generation sequencing showed no mesothelioma-associated tumour suppressor gene mutations, but deletion of CDKN2A and a rare TFG-ADGRG7 fusion both reported in pleural mesotheliomas, were detected. Clinicians should consider malignancy in case of discrepancy between symptoms and objective findings in scrotal conditions.

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