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. 2024 Feb 5;7(2):e2354470.
doi: 10.1001/jamanetworkopen.2023.54470.

Interpretation of Antibiotic Trials in Pediatric Pneumonia

Susan C Lipsett  1   2 , Alexander W Hirsch  1   2 , Richard G Bachur  1   2 , Mark I Neuman  1   2
Affiliations

Interpretation of Antibiotic Trials in Pediatric Pneumonia

Susan C Lipsett et al. JAMA Netw Open. .
No abstract available

Plain language summary

This cohort study assesses radiographic evidence of pneumonia and antibiotic use in children with clinically suspected community-acquired pneumonia.

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Conflict of interest statement

Conflict of Interest Disclosures: Dr Neuman reported serving on the World Health Organization Guideline Development Group for the Diagnosis and Management of Pneumonia and Diarrhea in Children; serving as an expert panel member of Infectious Diseases Society of America Clinical Practice Guideline for the Management of Community-Acquired Pneumonia in Children; and receiving royalties from Wolters Kluwer for contributions to UpToDate and from the American Academy of Pediatrics for being Associate Editor of Pediatrics.

References

    1. Pernica JM, Harman S, Kam AJ, et al. . Short-course antimicrobial therapy for pediatric community-acquired pneumonia: the SAFER randomized clinical trial. JAMA Pediatr. 2021;175(5):475-482. doi:10.1001/jamapediatrics.2020.6735 - DOI - PMC - PubMed
    1. Ginsburg AS, Mvalo T, Nkwopara E, et al. . Amoxicillin for 3 or 5 days for chest-indrawing pneumonia in Malawian children. N Engl J Med. 2020;383(1):13-23. doi:10.1056/NEJMoa1912400 - DOI - PMC - PubMed
    1. Bielicki JA, Stöhr W, Barratt S, et al. ; PERUKI, GAPRUKI, and the CAP-IT Trial Group . Effect of amoxicillin dose and treatment duration on the need for antibiotic re-treatment in children with community-acquired pneumonia: the CAP-IT randomized clinical trial. JAMA. 2021;326(17):1713-1724. doi:10.1001/jama.2021.17843 - DOI - PMC - PubMed
    1. Williams DJ, Creech CB, Walter EB, et al. ; The DMID 14-0079 Study Team . Short- vs standard-course outpatient antibiotic therapy for community-acquired pneumonia in children: the SCOUT-CAP randomized clinical Trial. JAMA Pediatr. 2022;176(3):253-261. doi:10.1001/jamapediatrics.2021.5547 - DOI - PMC - PubMed
    1. Lipsett SC, Monuteaux MC, Bachur RG, Finn N, Neuman MI. Negative chest radiography and risk of pneumonia. Pediatrics. 2018;142(3):e20180236. doi:10.1542/peds.2018-0236 - DOI - PubMed

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