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Review
. 2024 May;35(3):330-343.
doi: 10.1111/cyt.13363. Epub 2024 Feb 2.

Molecular testing in salivary gland cytopathology: A practical overview in conjunction with the Milan system

Anna Maria Carillo  1 , Caterina De Luca  1 , Pasquale Pisapia  1 , Elena Vigliar  1 , Kristian Ikenberg  2 , Sandra N Freiberger  2 , Giancarlo Troncone  1 , Niels J Rupp  2   3 , Claudio Bellevicine  1
Affiliations
Review

Molecular testing in salivary gland cytopathology: A practical overview in conjunction with the Milan system

Anna Maria Carillo et al. Cytopathology. 2024 May.

Abstract

Recently, significant advances in the molecular characterization of salivary gland neoplasms have facilitated the classification and diagnosis of specific diagnostic entities. In the highly challenging diagnostic scenario of salivary malignancies, molecular testing is increasingly being adopted in routine practice to refine the cytological diagnosis of salivary lesions. Here, we reviewed the most recent evidence in the field of salivary glands molecular cytopathology.

Keywords: FNA; gene fusions; molecular cytopathology; molecular testing; salivary glands.

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References

REFERENCES

    1. Layfield LJ, Gopez E, Hirschowitz S. Cost efficiency analysis for fine‐needle aspiration in the workup of parotid and submandibular gland nodules. Diagn. Cytopathol. 2006;34(11):734‐738.
    1. Rossi ED, Faquin WC, Baloch Z, et al. The Milan system for reporting salivary gland cytopathology: analysis and suggestions of initial survey. Cancer Cytopathol. 2017;125(10):757‐766.
    1. Song SJ, Shafique K, Wong LQ, LiVolsi VA, Montone KT, Baloch Z. The utility of the Milan system as a risk stratification tool for salivary gland fine needle aspiration cytology specimens. Cytopathology. 2019;30(1):91‐98.
    1. Viswanathan K, Sung S, Scognamiglio T, Yang GCH, Siddiqui MT, Rao RA. The role of the Milan system for reporting salivary gland cytopathology: a 5‐year institutional experience. Cancer Cytopathol. 2018;126(8):541‐551.
    1. Barbarite E, Puram SV, Derakhshan A, Rossi ED, Faquin WC, Varvares MA. A call for universal acceptance of the Milan system for reporting salivary gland cytopathology. Laryngoscope. 2020;130(1):80‐85.

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