Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2024;20(3):35-44.
doi: 10.2174/011573403X259676231222053709.

Emerging Strategies and Effective Prevention Measures for Investigating the Association Between Stroke and Sudden Cardiac Fatality

Affiliations
Review

Emerging Strategies and Effective Prevention Measures for Investigating the Association Between Stroke and Sudden Cardiac Fatality

H Nithesh Kumar et al. Curr Cardiol Rev. 2024.

Abstract

Stroke-related cardiac death is a significant concern for patients with stroke and their healthcare providers. It is a complex and multifaceted condition that requires careful management of both modifiable and non-modifiable risk factors. This review provides an overview of the pathophysiology, risk factors, and prevention strategies for stroke-related cardiac death. The review highlights the importance of identifying and managing modifiable risk factors such as hypertension, diabetes, and lifestyle factors, as well as non-modifiable risk factors such as age and genetics. Additionally, the review explores emerging strategies for prevention, including the use of wearable devices and genetic testing to identify patients at risk, stem cell therapy and gene therapy for cardiac dysfunction, and precision medicine for personalized treatment plans. Despite some limitations to this review, it provides valuable insights into the current understanding of stroke-related cardiac death and identifies important areas for future research. Ultimately, the implementation of evidence-based prevention strategies and personalized treatment plans has the potential to improve outcomes for patients with stroke and reduce the burden of stroke-related cardiac death in the population.

Keywords: Stroke; cardiac death; emerging strategies; gene therapy; genetic testing; precision medicine.; stem cell therapy; wearable devices.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest, financial or otherwise.

Figures

Fig. (1)
Fig. (1)
Shows a mechanism of neurogenic stress cardiomyopathy due to stroke.
Fig. (2)
Fig. (2)
Shows a diagram of how cardiac failure are caused after an ischemic stroke.

Similar articles

Cited by

References

    1. Centers for Disease Control and Prevention (CDC). Prevalence of coronary heart disease--United States, 2006-2010. MMWR Morb. Mortal. Wkly. Rep. 2011;60(40):1377–1381. - PubMed
    1. Centers for Disease Control and Prevention (CDC). Prevalence of stroke--United States, 2006-2010. MMWR Morb. Mortal. Wkly. Rep. 2012;61(20):379–382. - PubMed
    1. Kannel W.B. The Framingham Study: ITS 50-year legacy and future promise. J. Atheroscler. Thromb. 2000;6(2):60–66. doi: 10.5551/jat1994.6.60. - DOI - PubMed
    1. Lo E.H., Dalkara T., Moskowitz M.A. Mechanisms, challenges and opportunities in stroke. Nat. Rev. Neurosci. 2003;4(5):399–414. doi: 10.1038/nrn1106. - DOI - PubMed
    1. Zhang Z.G., Chopp M. Neurorestorative therapies for stroke: Underlying mechanisms and translation to the clinic. Lancet Neurol. 2009;8(5):491–500. doi: 10.1016/S1474-4422(09)70061-4. - DOI - PMC - PubMed