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Editorial
. 2024 Apr;30(2):174-176.
doi: 10.3350/cmh.2024.0082. Epub 2024 Feb 5.

The gene expression signature of metabolic dysfunction- associated steatotic liver disease from a multiomics perspective

Carlos Jose Pirola  1   2   3 , Silvia Sookoian  2   3   4
Affiliations
Editorial

The gene expression signature of metabolic dysfunction- associated steatotic liver disease from a multiomics perspective

Carlos Jose Pirola et al. Clin Mol Hepatol. 2024 Apr.
No abstract available

Keywords: Gene expression; HCC; MASH; MASLD; OMICS.

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Conflict of interest statement

Conflicts of Interest

The authors have no conflicts to disclose.

Comment on

References

    1. Sookoian S, Pirola CJ, Valenti L, Davidson NO. Genetic pathways in nonalcoholic fatty liver disease: insights from systems biology. Hepatology. 2020;72:330–346. - PMC - PubMed
    1. Sookoian S, Rosselli MS, Gemma C, Burgueño AL, Fernández Gianotti T, et al. Epigenetic regulation of insulin resistance in nonalcoholic fatty liver disease: impact of liver methylation of the peroxisome proliferator-activated receptor γ coactivator 1α promoter. Hepatology. 2010;52:1992–2000. - PubMed
    1. Pirola CJ, Sookoian S. Metabolic dysfunction-associated fatty liver disease: advances in genetic and epigenetic implications. Curr Opin Lipidol. 2022;33:95–102. - PubMed
    1. Pirola CJ, Salatino A, Fernández Gianotti T, Castaño GO, Garaycoechea M, Sookoian S. Cross talk between the liver microbiome and epigenome in patients with metabolic dysfunction-associated steatotic liver disease. EBioMedicine. 2024;101:104996. - PMC - PubMed
    1. Murphy SK, Yang H, Moylan CA, Pang H, Dellinger A, Abdelmalek MF, et al. Relationship between methylome and transcriptome in patients with nonalcoholic fatty liver disease. Gastroenterology. 2013;145:1076–1087. - PMC - PubMed