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Review
. 2024 Jan 4;16(1):e51681.
doi: 10.7759/cureus.51681. eCollection 2024 Jan.

Critical Correlation Between Obesity and Cardiovascular Diseases and Recent Advancements in Obesity

Affiliations
Review

Critical Correlation Between Obesity and Cardiovascular Diseases and Recent Advancements in Obesity

Mahesh Pakhare et al. Cureus. .

Abstract

Scientific literature has investigated and well-documented the complex relationship between obesity and cardiovascular diseases. Obese people are much more likely to have atrial fibrillation, dyslipidemia, diabetes, and coronary artery disease, among other cardiovascular conditions. Additionally, obesity poses a severe risk for diseases like hypertension, heart failure, and atherosclerotic heart diseases, affecting various aspects relating to their underlying mechanisms, diagnosis, and clinical effects. This article summarizes recent developments in our understanding of and response to obesity. Pharmacotherapy, gut microbiome research, bariatric surgery, digital health solutions, behavioral interventions, and precision medicine are just a few of the fields in which these developments have been made. While liposuction offers a less invasive option for redistributing volume and getting positive results, bariatric surgery remains the most effective treatment for severe obesity. Emphasis is placed on the pathophysiological mechanisms that underlie the complex interactions between obesity and a number of diseases, such as atrial fibrillation, diabetes, hypertension, dyslipidemia, and coronary artery disease. The significance of lifestyle changes in reducing the cardiovascular risks associated with obesity, such as atrial fibrillation and heart disease, is emphasized. To improve overall cardiovascular health and achieve better clinical outcomes, obesity must be promptly identified and actively managed. Investigations into how the gut microbiome affects obesity, the creation of novel pharmacological treatments for appetite suppression and metabolic enhancement, improvements in bariatric surgery methods that emphasize patient success and safety, as well as creative digital health solutions and behavioral treatments, are some examples of emerging research fields. In addition, precision medicine approaches, including the modulation of the gut microbiome through dietary changes and supplements, hold great promise in combating obesity and its associated comorbidities and have the potential to revolutionize the management of obesity by tailoring treatments to the specific needs of individual patients.

Keywords: bariatric surgery; cardiovascular disease; diabetes; dyslipidemia; gut microbiome; hypertension; liposuction; obesity.

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Conflict of interest statement

The authors have declared that no competing interests exist.

References

    1. The impact of obesity on the cardiovascular system. Csige I, Ujvárosy D, Szabó Z, Lőrincz I, Paragh G, Harangi M, Somodi S. J Diabetes Res. 2018;2018:3407306. - PMC - PubMed
    1. Prevention of diabetes and cardiovascular disease in obesity. La Sala L, Pontiroli AE. Int J Mol Sci. 2020;21:8178. - PMC - PubMed
    1. Recent advances in obesity: genetics and beyond. Cheung WW, Mao P. ISRN Endocrinol. 2012;2012:536905. - PMC - PubMed
    1. Six reasons why the waist-to-height ratio is a rapid and effective global indicator for health risks of obesity and how its use could simplify the international public health message on obesity. Ashwell M, Hsieh SD. Int J Food Sci Nutr. 2005;56:303–307. - PubMed
    1. Obesity and cardiovascular disease: a scientific statement from the American Heart Association. Powell-Wiley TM, Poirier P, Burke LE, et al. Circulation. 2021;143:0. - PMC - PubMed

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