Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Published Erratum
. 2024 Jan 19:15:1355200.
doi: 10.3389/fnagi.2023.1355200. eCollection 2023.

Corrigendum: Evaluation of ferritin and TfR level in plasma neural-derived exosomes as potential markers of Parkinson's disease

Zhi-Ting Chen #  1 , Chu-Zhui Pan #  2   3 , Xing-Lin Ruan #  1 , Li-Ping Lei  2   3 , Sheng-Mei Lin  2   3 , Yin-Zhou Wang  2   3 , Zhen-Hua Zhao  2   3
Affiliations
Published Erratum

Corrigendum: Evaluation of ferritin and TfR level in plasma neural-derived exosomes as potential markers of Parkinson's disease

Zhi-Ting Chen et al. Front Aging Neurosci. .

Abstract

[This corrects the article DOI: 10.3389/fnagi.2023.1216905.].

Keywords: Parkinson's disease; biomarker; exosome; ferritin; transferrin receptor.

PubMed Disclaimer

Figures

Figure 3
Figure 3
Comparation of ferritin and TfR in PD and controls, and ROC analysis of biomarkers for PD diagnosis. The box plots showed the comparison of the levels of ferritin (A) and TfR (B) in the two groups. *, P < 0.01. In the whole cohort, ferritin in plasma neural-derived exosomes provided an AUC of 0.73 (sensitivity = 67.4%, specificity = 79.4%) for PD versus controls (C). TfR performed similarly (AUC = 0.812, sensitivity = 86.0%, specificity = 70.6%) in the whole cohort (D). And, the combination of ferritin and TfR did not obviously improve the performance with AUC of 0.808 (sensitivity = 86.0%, specificity = 73.5%) (E).
See this image and copyright information in PMC

Erratum for

References

    1. Chawla S., Gulyani S., Allen RP., Earley C.J., Li X., Van Zijl P., et al. . (2019). Extracellular vesicles reveal abnormalities in neuronal iron metabolism in restless legs syndrome. Sleep 42, zsz079. 10.1093/sleep/zsz079 - DOI - PMC - PubMed
    1. Jimenez-Jimenez F. J., Alonso-Navarro H., Garcia-Martin E., Agundez J. A. G. (2021). Biological fluid levels of iron and iron-related proteins in Parkinson's disease: Review and meta-analysis. Eur. J. Neurol. 28, 1041–1055. 10.1111/ene.14607 - DOI - PubMed
    1. Shi M., Kovac A., Korff A., Cook T. J., Ginghina C., Bullock K. M., et al. . (2016). CNS tau efflux via exosomes is likely increased in Parkinson's disease but not in Alzheimer's disease. Alzheimers Dement. J. Alzheimers Assoc. 12, 1125–1131. 10.1016/j.jalz.2016.04.003 - DOI - PMC - PubMed
    1. Shi M., Liu C., Cook T. J., Bullock K. M., Zhao Y., Ginghina C., et al. . (2014). Plasma exosomal alpha-synuclein is likely CNS-derived and increased in Parkinson's disease. Acta Neuropathol. 128, 639–650. 10.1007/s00401-014-1314-y - DOI - PMC - PubMed

Publication types

LinkOut - more resources