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Review
. 2024 Jan 20;10(3):e24949.
doi: 10.1016/j.heliyon.2024.e24949. eCollection 2024 Feb 15.

Nanotechnology in toothpaste: Fundamentals, trends, and safety

Affiliations
Review

Nanotechnology in toothpaste: Fundamentals, trends, and safety

Mehdi Abedi et al. Heliyon. .

Abstract

Several studies have revealed that healthcare nanomaterials are widely used in numerous areas of dentistry, including prevention, diagnosis, treatment, and repair. Nanomaterials in dental cosmetics are utilized to enhance the efficacy of toothpaste and other mouthwashes. Nanoparticles are added to toothpastes for a variety of reasons, including dental decay prevention, remineralization, hypersensitivity reduction, brightening, and antibacterial qualities. In this review, the benefits and uses of many common nanomaterials found in toothpaste are outlined. Additionally, the capacity and clinical applications of nanoparticles as anti-bacterial, whitening, hypersensitivity, and remineralizing agents in the treatment of dental problems and periodontitis are discussed.

Keywords: Hydroxyapatite; Hypersensitivity; Nanoparticles; Remineralization; Toothpaste.

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Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Image 1
Graphical abstract
Fig. 1
Fig. 1
Nano-HAP toothpaste in reducing dental hypersensitivity.
Fig. 2
Fig. 2
Demineralization and Remineralization process.
Fig. 3
Fig. 3
The mechanism of action of HAP on biofilm management. Through its interaction with bacterial adhesion, HAP can bind to microorganisms and expelling them from the oral cavity. Additionally, the pellicle receptors' ability to bind to bacterial receptors is blocked by HAP.

References

    1. Pitts N.B., et al. Dental caries. Nat. Rev. Dis. Prim. 2017;3 - PubMed
    1. Sari M., et al. Development of a hydroxyapatite nanoparticle-based gel for enamel remineralization —a physicochemical properties and cell viability assay analysis. Dent. Mater. J. 2022;41(1):68–77. - PubMed
    1. Chen L., et al. Hydroxyapatite in oral care products-A review. Materials. 2021;14(17) - PMC - PubMed
    1. Carvalho T.S., et al. Consensus report of the European Federation of Conservative Dentistry: erosive tooth wear--diagnosis and management. Clin. Oral Invest. 2015;19(7):1557–1561. - PubMed
    1. Buedel S., et al. Impact of dentifrice abrasivity and remineralization time on erosive tooth wear in vitro. Am. J. Dent. 2018;31(1):29–33. - PubMed

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