Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2022 Mar;1(3):EVIDctw2100025.
doi: 10.1056/EVIDctw2100025. Epub 2022 Feb 22.

Data and Safety Monitoring Board Monitoring of Clinical Trials for Early Efficacy

Lori E Dodd  1 , Michael A Proschan  1
Affiliations
Review

Data and Safety Monitoring Board Monitoring of Clinical Trials for Early Efficacy

Lori E Dodd et al. NEJM Evid. 2022 Mar.

Abstract

DSMB Monitoring of Clinical Trials for Early EfficacyIn this article in the NEJM Evidence DSMB mini-series, Dodd and Proschan review the clinical, ethical, and statistical issues that confront a DSMB when trial data suggest that the treatment under test is highly efficacious. Examples of such trials are reviewed.

PubMed Disclaimer

MeSH terms

LinkOut - more resources