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Editorial
. 2022 Dec;1(12):EVIDe2200276.
doi: 10.1056/EVIDe2200276. Epub 2022 Nov 22.

Crossword Puzzles for Brain Training in Mild Cognitive Impairment

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Editorial

Crossword Puzzles for Brain Training in Mild Cognitive Impairment

Milap A Nowrangi et al. NEJM Evid. 2022 Dec.

Abstract

Given the increasing prevalence and public health impact of dementia, it is imperative that we identify prevention strategies. One approach, broadly termed brain training, can be defined as guided drill-and-practice mental exercises targeting cognitive domains. We have evidence suggesting that brain training may prevent dementia in cognitively intact adults, including the well-validated protective effect of education early in life and the results of the ACTIVE (Advanced Cognitive Training for Independent and Vital Elderly) trial,1 which showed not only a long-term cognitive benefit of training in processing speed, but also a possible decrease in dementia incidence and transfer of cognitive benefits to performance in everyday functioning (as measured by performance on instrumental activities of daily living).

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