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Review
. 2025;19(3):407-433.
doi: 10.2174/0118722105264531231205042817.

Role of Nanoformulations in the Treatment of Lung Cancer

Affiliations
Review

Role of Nanoformulations in the Treatment of Lung Cancer

Parijat Pandey et al. Recent Pat Nanotechnol. 2025.

Abstract

Lung cancer is the second deadliest disease in the world. A major portion of deaths related to cancer are due to lung cancer in both males and females. Interestingly, unbelievable advances have occurred in recent years through the use of nanotechnology and development in both the diagnosis and treatment of lung cancer. Due to their in vivo stability, the nanotechnology-based pharmacological system gained huge attractiveness, solubility, absorption from the intestine, pharmacological effectiveness, etc. of various anticancer agents. However, this field needs to be utilized more to get maximum results in the treatment of lung cancer, along with wider context medicines. In the present review, authors have tried to concentrate their attention on lung cancer`s difficulties along with the current pharmacological and diagnostic situation, and current advancements in approaches based on nanotechnology for the treatment and diagnosis of lung cancer. While nanotechnology offers these promising avenues for lung cancer diagnosis and treatment, it is important to acknowledge the need for careful evaluation of safety, efficacy, and regulatory approval. With continued research and development, nanotechnology holds tremendous potential to revolutionize the management of lung cancer and improve patient outcomes. The review also highlights the involvement of endocrine systems, especially estrogen in lung cancer proliferation. Some of the recent clinical trials and patents on nanoparticle-based formulations that have applications in the treatment and diagnosis of lung cancer are also discussed.

Keywords: Nanotechnology; clinical trials; diagnosis; estrogen.; lung cancer; nanoformulations.

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References

    1. Bayda S.; Adeel M.; Tuccinardi T.; Cordani M.; Rizzolio F.; The history of nanoscience and nanotechnology: From chemical-physical applications to nanomedicine. Molecules 2019,25(1),112-126 - DOI - PubMed
    1. Purohit D.; Manchanda D.; Makhija M.; Rathi J.; Verma R.; Kaushik D.; Pandey P.; An overview of the recent developments and patents in the field of pharmaceutical nanotechnology. Recent Pat Nanotechnol 2021,15(1),15-34 - DOI - PubMed
    1. Oberdörster G.; Maynard A.; Donaldson K.; Castranova V.; Fitzpatrick J.; Ausman K.; Carter J.; Karn B.; Kreyling W.; Lai D.; Olin S.; Monteiro-Riviere N.; Warheit D.; Yang H.; Principles for characterizing the potential human health effects from exposure to nanomaterials: Elements of a screening strategy. Part Fibre Toxicol 2005,2(1),8-43 - DOI - PubMed
    1. Varma A.; Mukasyan A.S.; Rogachev A.S.; Manukyan K.V.; Solution combustion synthesis of nanoscale materials. Chem Rev 2016,116(23),14493-14586 - DOI - PubMed
    1. Barhoum A.; García-Betancourt M.L.; Jeevanandam J.; Hussien E.A.; Mekkawy S.A.; Mostafa M.; Omran M.M.; S Abdalla M.; Bechelany M.; Review on natural, incidental, bioinspired, and engineered nanomaterials: History, definitions, classifications, synthesis, properties, market, toxicities, risks, and regulations. Nanomaterials 2022,12(2),177-225 - DOI - PubMed

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