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Review
. 2024 Jan 3:11:1301137.
doi: 10.3389/fped.2023.1301137. eCollection 2023.

Advances in genetic factors of adolescent idiopathic scoliosis: a bibliometric analysis

Xiaowei Jiang  1 , Fuyun Liu  1 , Mingxuan Zhang  1 , Weiming Hu  1 , Yufeng Zhao  1 , Bing Xia  1 , Ke Xu  1
Affiliations
Review

Advances in genetic factors of adolescent idiopathic scoliosis: a bibliometric analysis

Xiaowei Jiang et al. Front Pediatr. .

Abstract

Objective: This study offers a bibliometric analysis of the current situation, hotspots, and cutting-edge domains of genetic factors of adolescent idiopathic scoliosis (AIS).

Methods: All publications related to genetic factors of AIS from January 1, 1992, to February 28, 2023, were searched from the Web of Science. CiteSpace software was employed for bibliometric analysis, collecting information about countries, institutions, authors, journals, and keywords of each article.

Results: A cumulative number of 308 articles have been ascertained. Since 2006, publications relating to genetic factors of AIS have significantly increased. China leads in both productivity and influence in this area, with the Chinese Academy of Medical Sciences being the most productive institution. The most prolific scholars in this field are Y. Qiu and Z. Z. Zhu. The publications that contributed the most were from Spine and European Spine Journal. The most prominent keywords in the genetic factors of AIS were "fibrillin gene", "menarche", "calmodulin", "estrogen receptor gene", "linkage analysis", "disc degeneration", "bone mineral density", "melatonin signaling dysfunction", "collagen gene", "mesenchymal stem cell", "LBX1", "promoter polymorphism", "Bone formation", "cerebrospinal fluid flow" and "extracellular matrix".

Conclusion: This analysis provides the frontiers and trends of genetic factors in AIS, including relevant research, partners, institutions and countries.

Keywords: CiteSpace; adolescent idiopathic scoliosis; advances; bibliometric analysis; genetic factors.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
The annual patterns of publications.
Figure 2
Figure 2
The geographic distribution of publications. Darker colors indicate greater number of publications.
Figure 3
Figure 3
Collaboration network of productive countries/regions. Nodes represent countries/regions, and lines indicate co-citation relationships. Node colors correspond to different years. Larger nodes indicate higher publication numbers.
Figure 4
Figure 4
Collaboration network of productive institutions. Nodes represent institutions, lines represent co-citation relationships. Node colors indicate different years. Node size reflects publication numbers.
Figure 5
Figure 5
Collaboration network of cited journals. Nodes represent journals, lines represent co-citation relationships. Node colors indicate different years. Node size reflects the number of co-citations.
Figure 6
Figure 6
Collaboration network of productive authors. Nodes represent authors, lines represent collaborations. Node colors indicate different years. Node size reflects publication count.
Figure 7
Figure 7
Collaboration network of cited authors. Nodes represent co-cited authors. Lines represent co-citation relationships. Node colors indicate different years. Node size reflects the number of co-citations.
Figure 8
Figure 8
The network of cited references. Nodes represent references, lines represent co-citation relationships. Node colors indicate different years. Node size reflects the number of co-citations.
Figure 9
Figure 9
The network of keywords. Nodes represent keywords, lines represent co-occurrence relationships. Colors in the nodes indicate different years. Node size reflects its frequency.
Figure 10
Figure 10
The cluster view map. Each grid contains a cluster of locations. The lower the number, the higher the number of keywords included in the clusters.
Figure 11
Figure 11
Top 71 keywords with the strongest citation bursts. The red bar is the burst phase.
See this image and copyright information in PMC

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