Aggressive Multiple Central Giant Cell Granulomas of the Jaws
- PMID: 38322589
- PMCID: PMC10845258
- DOI: 10.1155/2023/5410229
Aggressive Multiple Central Giant Cell Granulomas of the Jaws
Abstract
Central giant cell granuloma (CGCG) is considered a benign intraosseous lesion with a varied range of clinical features in two subtypes, including aggressive and non-aggressive lesions. This study presents a 9-year-old boy with multiple bilateral CGCG in the mandible without any systemic disease or specific syndrome. Clinical, radiographic, and histopathological findings demonstrated the aggressive lesions. It is discussed how the differential diagnosis and treatment can be determined based on the patient's age as well as the size and manner of the lesion.
Copyright © 2023 Farnoush Mohammadi et al.
Conflict of interest statement
The authors declare(s) that they have no conflicts of interest.
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References
-
- WHO Classification of Tumours, WHO Classification of Head and Neck Tumours: International Agency for Research on Cancer (IARC) 2017.
-
- Lone P. A., Ahmed T., Ahmed T., Kumar V. Clinicopathologic features of central & peripheral giant cell lesions of oral cavity: our clinical experience. International Journal of Applied Research . 2016;2(10):29–33.
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