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Meta-Analysis
. 2024 Feb 2:36:e1788.
doi: 10.1590/0102-672020230070e1788. eCollection 2024.

IMPACT OF HELICOBACTER PYLORI ON EARLY POSTOPERATIVE COMPLICATIONS AFTER SLEEVE GASTRECTOMY: A SYSTEMATIC REVIEW AND META-ANALYSIS

Anna Carolina Batista Dantas  1 , Vitoria Ramos Jayme  2 , Kaique Flavio Xavier Cardoso Filardi  2 , Denis Pajecki  1 , Marco Aurelio Santo  1
Affiliations
Meta-Analysis

IMPACT OF HELICOBACTER PYLORI ON EARLY POSTOPERATIVE COMPLICATIONS AFTER SLEEVE GASTRECTOMY: A SYSTEMATIC REVIEW AND META-ANALYSIS

Anna Carolina Batista Dantas et al. Arq Bras Cir Dig. .

Abstract
in English, Portuguese

The impact of Helicobacter pylori (HP) on postoperative outcomes after sleeve gastrectomy (SG) is still controversial. A systematic review and meta-analysis were performed to compare the incidence of early complications after SG between HP-positive and HP-negative patients. Eight retrospective comparative studies were included, comprising 4,877 individuals. The prevalence of HP infection in gastric resected specimens ranged from 7.77 to 43.20%. There were no statistically significant differences between groups for overall complications (OR 1.46; 95%CI 0.95-2.23; p=0.08), bleeding (OR 1.35; 95%CI 0.70-2.60; p=0.38), and leak (OR 1.74; 95%CI 0.80-3.81; p=0.17) rates. The need for routine screening and treatment of HP infection before SG remains ambiguous.

O impacto do Helicobacter pylori (HP) nos desfechos pós-operatórios da Gastrectomia Vertical (GV) ainda é controverso. Uma revisão sistemática e meta-análise foram realizadas para comparar a incidência de complicações pós-operatórias depois da GV entre pacientes HP-positivo e HP-negativo. Oito estudos comparativos retrospectivos foram incluídos, englobando 4.877 indivíduos. A prevalência de infecção por HPnos espécimes gástricos ressecados variou de 7,77 a 43,20%. Não houve diferença estatística significante entre os grupos para complicações gerais (OR 1,46; IC95% 0,95–2,23; p=0,08), sangramento (OR 1,35; IC95% 0,70–2,60; p=0,38), e fístula (OR 1,74; IC95% 0,80–3,81; p=0,17). A necessidade de rastreio e erradicação rotineira do HP antes da GV permanece ambígua.

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Conflict of interest statement

Conflict of interests: None

Figures

Figure 1
Figure 1. Flow diagram of study selection.
Figure 2
Figure 2. Overall complication rates for HP-positive vs. HP-negative groups.
Figure 3
Figure 3. Bleeding rates for HP-positive vs. HP-negative groups.
Figure 4
Figure 4. Leak rates for HP-positive vs. HP-negative groups.
See this image and copyright information in PMC

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