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Editorial
. 2024 Feb 13;83(6):679-681.
doi: 10.1016/j.jacc.2023.12.003.

Thrombosis, Bleeding, and the Promise of Factor XI(a) Inhibition

Felicita Andreotti  1 , Massimo Massetti  2 , Gilles Montalescot  3
Affiliations
Free article
Editorial

Thrombosis, Bleeding, and the Promise of Factor XI(a) Inhibition

Felicita Andreotti et al. J Am Coll Cardiol. .
Free article
No abstract available

Keywords: asundexian; atrial fibrillation; bleeding; factor XI inhibitor; myocardial infarction; placebo; stroke.

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Conflict of interest statement

Funding Support and Author Disclosures Dr Andreotti has received consulting/lecture fees from Amgen, AstraZeneca, Bayer, BMS/Pfizer, Daiichi-Sankyo, and Servier. Dr Montalescot has received research or educational grants to the institution or consulting/lecture fees from Abbott, Amgen, AstraZeneca, Bayer, Boehringer Ingelheim, Boston Scientific, Bristol Myers Squibb, Cell-Prothera, Europa, IRIS-Servier, Novartis, Medtronic, MSD, Pfizer, Quantum Genomics, and Sanofi-Aventis. Dr Massetti has reported that he has no relationships relevant to the contents of this paper to disclose.

Comment on

  • Bleeding Outcomes in Patients Treated With Asundexian in Phase II Trials.
    Eikelboom JW, Mundl H, Alexander JH, Caso V, Connolly SJ, Coppolecchia R, Gebel M, Hart RG, Holberg G, Keller L, Patel MR, Piccini JP, Rao SV, Shoamanesh A, Tamm M, Viethen T, Yassen A, Bonaca MP. Eikelboom JW, et al. J Am Coll Cardiol. 2024 Feb 13;83(6):669-678. doi: 10.1016/j.jacc.2023.12.004. J Am Coll Cardiol. 2024. PMID: 38325992 Clinical Trial.

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