Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2024 Nov;202(11):5235-5250.
doi: 10.1007/s12011-024-04076-w. Epub 2024 Feb 8.

Impact of Trace Mineral Source and Phytase Supplementation on Prececal Phytate Degradation and Mineral Digestibility, Bone Mineralization, and Tissue Gene Expression in Broiler Chickens

Hanna Philippi  1 , Vera Sommerfeld  1 , Alessandra Monteiro  2 , Markus Rodehutscord  3 , Oluyinka A Olukosi  4
Affiliations

Impact of Trace Mineral Source and Phytase Supplementation on Prececal Phytate Degradation and Mineral Digestibility, Bone Mineralization, and Tissue Gene Expression in Broiler Chickens

Hanna Philippi et al. Biol Trace Elem Res. 2024 Nov.

Erratum in

Abstract

The objective of this study was to determine how different sources of Zn, Mn, and Cu in the feed without and with phytase affect prececal myo-inositol hexakisphosphate (InsP6) breakdown to myo-inositol (MI), prececal P digestibility, bone mineralization, and expression of mineral transporters in the jejunum of broiler chickens. A total of 896 male broiler chicks (Cobb 500) were distributed to 7 diets with 8 replicate pens (16 birds per floor pen). Experimental diets were fed from day 0 to 28. Diets were without or with phytase supplementation (0 or 750 FTU/kg) and were supplemented with three different trace mineral sources (TMS: sulfates, oxides, or chelates) containing 100 mg/kg Zn, 100 mg/kg Mn, and 125 mg/kg Cu. Prececal InsP6 disappearance and P digestibility were affected by interaction (phytase × TMS: P ≤ 0.010). In diets without phytase supplementation, prececal InsP6 disappearance and P digestibility were greater (P ≤ 0.001) in birds fed chelated minerals than in birds fed sulfates or oxides. However, no differences were observed between TMS in diets with phytase supplementation. Ileal MI concentration was increased by exogenous phytase but differed depending on TMS (phytase × TMS: P ≤ 0.050). Tibia ash concentration as well as Zn and Mn concentration in tibia ash were increased by phytase supplementation (P < 0.010), but the Cu concentration in tibia ash was not (P > 0.050). Gene expression of the assayed mineral transporters in the jejunum was not affected by diet (P > 0.050), except for Zn transporter 5 (phytase × TMS: P = 0.024). In conclusion, the tested TMS had minor effects on endogenous phytate degradation in the digestive tract of broiler chickens. However, in phytase-supplemented diets, the choice of TMS was not relevant to phytate degradation under the conditions of this study.

Keywords: Bone mineralization; Phytase; Phytate degradation; Trace mineral source.

PubMed Disclaimer

Conflict of interest statement

Alessandra Monteiro is an employee of Animine (FR). The authors declare no conflict of interest.

References

    1. Zeigler TR, Leach RM, Norris LC, Scott ML (1961) Zinc requirement of the chick: factors affecting requirement. Poult Sci 40:1584–1593. 10.3382/ps.0401584
    1. Suttle NF (2022) Mineral nutrition of livestock, 5th edn. CABI, Wallingford
    1. National Research Council (1994) Nutrient requirements of poultry, 9th edn. National Academies Press, Washington, DC
    1. Hamdi M, Solà D, Franco R, Durosoy S, Roméo A, Pérez JF (2018) Including copper sulphate or dicopper oxide in the diet of broiler chickens affects performance and copper content in the liver. Anim Feed Sci Technol 237:89–97. 10.1016/j.anifeedsci.2018.01.014
    1. Rodehutscord M, Sommerfeld V, Kühn I, Bedford MR (2022) Phytases Potential and limits of phytate destruction in the digestive tract of pigs and poultry. In: Bedford et al (eds) Enzymes in farm animal nutrition, 3rd edn. CABI, Wallingford, pp 124–152