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Meta-Analysis
. 2024 Apr;38(4):1667-1684.
doi: 10.1007/s00464-023-10659-w. Epub 2024 Feb 8.

Laparoscopic appendectomy with single port vs conventional access: systematic review and meta-analysis of randomized clinical trials

Roberto Cirocchi  1 , Maria Chiara Cianci  2 , Lavinia Amato  3 , Luca Properzi  4 , Massimo Buononato  3 , Vanessa Manganelli Di Rienzo  5 , Giovanni Domenico Tebala  6 , Stefano Avenia  5 , Ruggero Iandoli  7 , Alberto Santoro  8 , Nereo Vettoretto  9 , Riccardo Coletta  2 , Antonino Morabito  2
Affiliations
Meta-Analysis

Laparoscopic appendectomy with single port vs conventional access: systematic review and meta-analysis of randomized clinical trials

Roberto Cirocchi et al. Surg Endosc. 2024 Apr.

Erratum in

Abstract

Background: Conventional three-access laparoscopic appendectomy (CLA) is currently the gold standard treatment, however, Single-Port Laparoscopic Appendectomy (SILA) has been proposed as an alternative. The aim of this systematic review/meta-analysis was to evaluate safety and efficacy of SILA compared with conventional approach.

Methods: Per PRISMA guidelines, we systematically reviewed randomised controlled trials (RCTs) comparing CLA vs SILA for acute appendicitis. The randomised Mantel-Haenszel method was used for the meta-analysis. Statistical data analysis was performed with the Review Manager software and the risk of bias was assessed with the Cochrane "Risk of Bias" assessment tool.

Results: Twenty-one studies (RCTs) were selected (2646 patients). The operative time was significantly longer in the SILA group (MD = 7,32), confirmed in both paediatric (MD = 9,80), (Q = 1,47) and adult subgroups (MD = 5,92), (Q = 55,85). Overall postoperative morbidity was higher in patients who underwent SILA, but the result was not statistically significant. In SILA group were assessed shorter hospital stays, fewer wound infections and higher conversion rate, but the results were not statistically significant. Meta-analysis was not performed about cosmetics of skin scars and postoperative pain because different scales were used in each study.

Conclusions: This analysis show that SILA, although associated with fewer postoperative wound infection, has a significantly longer operative time. Furthermore, the risk of postoperative general complications is still present. Further studies will be required to analyse outcomes related to postoperative pain and the cosmetics of the surgical scar.

Keywords: Acute appendicitis; Convectional access laparoscopic appendicectomy; Laparoscopic appendicectomy; Meta-analysis; Single-port laparoscopic appendicectomy.

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Figures

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PRISMA flowchart
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Risk of bias—RCTs
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Postoperative complications
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Operative time
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Incidence of laparotomic conversions
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Surgical wound infections
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Length of hospital stay
See this image and copyright information in PMC

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