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Case Reports
. 1979 Jul;12(1):32-7.

Membranous glomerulonephritis in congenital syphilis

A Losito, E Bucciarelli, F Massi-Benedetti, M Lato
  • PMID: 383337
Case Reports

Membranous glomerulonephritis in congenital syphilis

A Losito et al. Clin Nephrol. 1979 Jul.

Abstract

The glomerulonephritis of congenital syphilis is thought to be immune-complex mediated. We describe a case of C. S. in whom the only manifestation was a glomerulonephritis. Immunopathogenic studies allowed the identification of treponemal antigen in glomeruli. The elution of immunoglobulins from renal tissue showed that glomerular deposits contained antitreponemal antibodies. Cryoglobulins with antitreponemal activity were also isolated from the patient's serum.

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