SERCA2a microdomain cAMP changes in heart failure with preserved ejection fraction

Michael Gotthardt^{1

2

3}, Stephan E Lehnart^{4

5

6

7

8}

Affiliations

¹ Translational Cardiology and Functional Genomics, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Robert-Rössle-Strasse 10, 13125 Berlin, Germany.
² Department of Cardiology, Charité-Universitätsmedizin Berlin, Berlin, Germany.
³ DZHK (German Centre for Cardiovascular Research) partner site Berlin, Robert-Rössle-Strasse 10, 13125 Berlin, Germany.
⁴ Department of Cardiology and Pneumology, Heart Research Center Göttingen, University Medical Center Göttingen, Robert-Koch-Str. 42a, 37075 Göttingen, Germany.
⁵ Collaborative Research Center SFB1002 'Modulatory Units in Heart Failure', University of Göttingen, Robert-Koch-Str. 40, 37073 Göttingen, Germany.
⁶ Collaborative Research Center SFB1190 'Compartmental Gates and Contact Sites in Cells', University of Göttingen, Humboldtallee 23, 37073 Göttingen, Germany.
⁷ Cluster of Excellence 'Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells' (MBExC2067), University of Göttingen, Robert-Koch-Str. 40, 37075 Göttingen, Germany.
⁸ DZHK (German Centre for Cardiovascular Research) partner site Göttingen, 37075 Göttingen, Robert-Koch-Str. 40, Germany.

Editorial

Michael Gotthardt et al. Cardiovasc Res. 2024.

. 2024 Mar 14;120(3):220-222.

doi: 10.1093/cvr/cvae030.

Michael Gotthardt^{1

2

3}, Stephan E Lehnart^{4

5

6

7

8}

¹ Translational Cardiology and Functional Genomics, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Robert-Rössle-Strasse 10, 13125 Berlin, Germany.
² Department of Cardiology, Charité-Universitätsmedizin Berlin, Berlin, Germany.
³ DZHK (German Centre for Cardiovascular Research) partner site Berlin, Robert-Rössle-Strasse 10, 13125 Berlin, Germany.
⁴ Department of Cardiology and Pneumology, Heart Research Center Göttingen, University Medical Center Göttingen, Robert-Koch-Str. 42a, 37075 Göttingen, Germany.
⁵ Collaborative Research Center SFB1002 'Modulatory Units in Heart Failure', University of Göttingen, Robert-Koch-Str. 40, 37073 Göttingen, Germany.
⁶ Collaborative Research Center SFB1190 'Compartmental Gates and Contact Sites in Cells', University of Göttingen, Humboldtallee 23, 37073 Göttingen, Germany.
⁷ Cluster of Excellence 'Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells' (MBExC2067), University of Göttingen, Robert-Koch-Str. 40, 37075 Göttingen, Germany.
⁸ DZHK (German Centre for Cardiovascular Research) partner site Göttingen, 37075 Göttingen, Robert-Koch-Str. 40, Germany.

No abstract available

Conflict of interest statement

Conflict of interest: none declared.

Remodelling of cAMP dynamics within the SERCA2a microdomain in heart failure with preserved ejection fraction caused by obesity and type 2 diabetes.
Lai P, Hille SS, Subramanian H, Wiegmann R, Roser P, Müller OJ, Nikolaev VO, De Jong KA. Lai P, et al. Cardiovasc Res. 2024 Mar 14;120(3):273-285. doi: 10.1093/cvr/cvad178. Cardiovasc Res. 2024. PMID: 38099489 Free PMC article.