Pathological findings associated with the updated European Society of Cardiology 2022 guidelines for preoperative cardiac testing: an observational cohort modelling study
Collaborators
-
MET-REPAIR investigators:
Johann Kemper 25 , Lena Kohaupt 25 , Jette Witzler 25 , Michael Tuzhikov 25 , Sebastian Roth 25 , Alexandra Stroda 25 , René M'Pembele 25 , Theresa Tenge 25 , Cornelia Schultze 26 , Nele Verbarg 26 , Christian Gehrke 26 , Anna Katharina Klemann 26 , Friederike Hagebölling 26 , Svenja Albrecht 27 , Jakob Stroeder 27 , Ann-Kristin Schubert 27 , Florian Espeter 28 , Benedikt Russe 28 , Markus A Weigand 28 , Lars Bergmann 29 , Matthias Unterberg 29 , Petra Bischoff 30 , Raphael Pirzer 31 , Patric Rene Rach 31 , Klaus Ott 31 , Alexander Zarbock 32 , Ana Kowark 33 , Claudia Neumann 34 , Bahareh Marchand 34 , Christoph Sponholz 35 , Henrik Rueffert 36 , Mira Kramer 37 , Kai Zacharowski 38 , Patrick Meybohm 38 , Simone Lindau 38 , Patrick Meybohm 39 , Melissa Carollo 40 , Cecilia Novazzi 40 , Fiorenza Toso 40 , Alessandro Bacuzzi 40 , Riccardo Ragazzi 41 , Carlo Alberto Volta 41 , Francesco De Giorgi 41 , Barbara Bacer 42 , Antonio Federico 42 , Davide Chiumello 43 , Luigi Vetrugno 44 , Alberto Castella 45 , Simonetta Tesoro 46 , Antonella Cotoia 47 , Elena Bignami 48 , Agrippino Bellissima 49 , Andrea Cortegiani 50 , Marco Crisman 51 , Arturo Toninelli 52 , Ornella Piazza 53 , Lucia Mirabella 54 , Matteo Bossolasco 55 , Francesco Bona 56 , Juan Manuel Perdomo 57 , Miquel Coca-Martinez 57 , Albert Carramiñana 57 , Marta Giné Servén 58 , Astrid Batalla González 58 , José Maria Gil Sánchez 58 , Ángel Becerra-Bolaños 59 , Aurelio Rodríguez-Pérez 59 , Anna Artigas Soler 60 , Morena Basso 60 , Anna Peig Font 60 , Diana Vernetta 61 , Julia Hernando Santos 62 , Enrique Alday Muñoz 62 , Mercedes Cabellos Olivares 63 , Gregorio Marco 64 , Maria Bermudez Lopez 65 , Javier Barrio 66 , María Isabel Forés 67 , Estefanía Boix 67 , Mercedes Ayuso 68 , Bogdan Sorel Petre 69 , Ioana Sorina Oprea 69 , Mihai Dan Latiș 69 , Simona Margarit 70 , Horatiu Vasian 70 , Dana Tomescu 71 , Iulia Cîndea 72 , Dan Sebastian Dirzu 73 , Sanda-Maria Copotoiu 74 , Alida Moise 75 , Serban Bubenek-Turconi 76 , Liana Valeanu 76 , Patrick Mark Wanner 77 , Mirjana Djurdjevic 77 , Sandra Nuth 77 , Esther Seeberger 78 , Nicolai Goettel 78 , Firmin Kamber 78 , Michael Thomas Ganter 79 , Thomas Jan Gerber 79 , Daniela Schneebeli 79 , Andreas Pregernig 80 , Sina Grape 81 , Simon Tomala 82 , Bernardo Bollen Pinto 82 , Maciej Żukowski 83 , Małgorzata Zegan-Barańska 83 , Igor Karolak 83 , Lukasz Krzych 84 , Szymon Czajka 84 , Dorota Studzińska 85 , Anna Kluzik 86 , Tomasz Koszel 86 , Izabela Pabjańczyk 87 , Anna Gajdosz 88 , Suheyla Karadag Erkoc 89 , Basak Ceyda Meco 89 , Ahmet Kemalettin Koltka 90 , Muserref Beril Dincer 90 , Perihan Ekmekçi 91 , Kemal Tolga Saracoglu 92 , Filiz Alkaya Solmaz 93 , Menekse Ozcelik 94 , Oguzhan Arun 95 , Ozlem Korkmaz Dilmen 96 , Benedikt Preckel 97 , Markus W Hollmann 97 , Yannick Hazen 98 , Hans Donald de Boer 99 , Anne Epema 100 , Seppe Koopman 101 , Felix Van Lier 102 , Rita Pinto 103 , André Carrão 103 , Daniel Ribeiro 103 , Joana Mourão 104 , Miguel Coelho 105 , Nuno Losa 106 , Nuno Santos 107 , Luis Cabral 107 , Diana Afonso 108 , Sérgio Zenha 109 , Cristina Ramos 110 , Carla Hipólito 111 , Maria Vasilaki 112 , Antonia Andreeva 112 , Donika Zaimi 113 , Athanasios Chalkias 114 , Maria Spyraki 115 , Martina Rekatsina 116 , Georgia Tsaousi 117 , Anthony Short 118 , Sonja Meier 119 , Thumuluru Kavitha Madhuri 120 , Scott Latham 121 , James Knock 122 , Andrew Drummond 123 , Fiona Ramsden 124 , Agnieszka Kubisz-Pudelko 125 , James Walker 126 , Iain Moppett 127 , Louise White 128 , Matthew Jackson 129 , Henrik Reschreiter 130 , Richard Innes 131 , Michelle Chew 132 , Sigridur Kalman 133 , Jakob Wallden 134 , Anna Schening 135 , Lina Jonikaite 136 , Anna Enlund 137 , Luc De Baerdemaeker 138 , Stuart Morrison 139 , Steffen Rex 140 , Alexandros Alexis 141 , Viktoria E Khoronenko 142 , Alexey Ovezov 143 , Vladislav Belskii 144 , Kseniya Kaznacheeva 144 , Alexey Gritsan 145 , Biljana Kuzmanovska 146 , Liljana Malinovska-Nikolovska 147 , Stjepan Barisin 148 , Peter Poredos 149 , Daniela Arabadzhieva 150 , Dragana Unic-Stojanovic 151 , Mladjan Golubović 152 , Edith Fleischmann 153 , Oskar Kotzinger 154 , Marc Danguy Des Deserts 155 , Nicolas Ducrocq 156 , Donal J Buggy 157 , Jean François Bonnet 157 , Barbara Cusack 157 , Paul Calleja 158 , Antigona Hasani 159 , Rajmonda Nallbani 159
Affiliations
- 1 Department of Anaesthesiology, University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf, Germany. Electronic address: Alexandra.stroda@med.uni-duesseldorf.de.
- 2 Clinic for Anaesthesia, Intermediate Care, Prehospital Emergency Medicine and Pain Therapy, University Hospital Basel, Basel, Switzerland.
- 3 Department of Anaesthesia and Intensive Care, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
- 4 Center for Intensive Care and Perioperative Medicine, Jagiellonian University Medical College, Kraków, Poland.
- 5 Department of Anaesthesiology and Peri-operative Medicine, Ghent University Hospital, Ghent University, Ghent, Belgium.
- 6 Division of Anaesthesiology, Intensive Care, Rescue and Pain Medicine, Kantonsspital St. Gallen, St. Gallen, Switzerland.
- 7 Institute of Anaesthesiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
- 8 Department of Translational Medicine, University of Ferrara, Ferrara, Italy.
- 9 Department of Anaesthesia, Hospital Clinic of Barcelona, Universidad de Barcelona, Barcelona, Spain.
- 10 Department of Anaesthesiology and Intensive Care Medicine, Klinik Hirslanden, Zurich, Switzerland.
- 11 Department of Anaesthesiology, Moscow Regional Research Clinical Institute, Moscow, Russia.
- 12 Department of Anaesthesiology and ICU, Ankara University Medical School, Ankara, Turkey.
- 13 Department of Anaesthesiology, University Medical Center Utrecht, Utrecht, The Netherlands.
- 14 Department of Anaesthesiology, Hospital Beatriz Ângelo, Loures, Portugal.
- 15 Aretaieion University Hospital National and Kapodistrian University of Athens, Athens, Greece.
- 16 Department of Perioperative Medicine and Intensive Care, Karolinska Hospital and Institution for Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.
- 17 Department of Anaesthesiology and Intensive Care Medicine, Hannover Medical School, Hannover, Germany.
- 18 Anesthesia and Intensive Care Department, University Hospital, Varese, Italy.
- 19 Department of Anaesthesiology, Intensive Therapy and Pain Management, Pomeranian Medical University, Szczecin, Poland.
- 20 Department of Anaesthesiology, Heidelberg University Hospital, Heidelberg, Germany.
- 21 Anesthesia and Intensive Care Department III, Carol Davila University of Medicine and Pharmacy Bucharest, Central Military Emergency University Hospital "Dr. Carol Davila Bucharest", Bucharest, Romania.
- 22 Department of Anaesthesiology, Mater University Hospital, Dublin, Ireland.
- 23 Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK.
- 24 Department of Anaesthesiology, University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf, Germany; CARID, Cardiovascular Research Institute Düsseldorf, Medical Faculty and University Hospital Düsseldorf, Heinrich-Heine University Düsseldorf, Düsseldorf, Germany.
- 25 Universitätsklinikum Düsseldorf, Germany.
- 26 Hannover Medical School, Germany.
- 27 University Hospital Marburg, Germany.
- 28 Heidelberg University Hospital, Germany.
- 29 University Hospital Knappschaftskrankenhaus Bochum, Germany.
- 30 Marien Hospital Herne, Ruhr University Bochum, Germany.
- 31 Universitätsklinikum Augsburg, Germany.
- 32 University Hospital Muenster, Germany.
- 33 University Hospital RWTH Aachen, Germany.
- 34 University Hospital Bonn, Germany.
- 35 Jena University Hospital, Germany.
- 36 Helios Klinik Schkeuditz, Germany.
- 37 University Witten / Herdecke - Hospital Center Merheim Cologne, Germany.
- 38 University Hospital Frankfurt, Germany.
- 39 University Hospital Würzburg, Germany.
- 40 ASST Settelaghi - Ospedale di Circolo e Fondazione Macchi, Varese, Italy.
- 41 Arcispedale Sant'Anna Ferrara, Italy.
- 42 Azienda USL Di Bologna, Italy.
- 43 ASST Santi Paolo e Carlo, Italy.
- 44 Asuiud, Italy.
- 45 Ospedale San Raffaele IRCCS, Italy.
- 46 University of Perugia Hospital Santa Maria della Misericordia, Italy.
- 47 Hospital of Foggia, Italy.
- 48 Azienda Ospedaliero universitaria di Parma, Italy.
- 49 Arnas Garibaldi, Italy.
- 50 University Hospital Policlinico P. Giaccone, Italy.
- 51 Azienda Sanitaria Universitaria Integrata di Trieste, Italy.
- 52 ASST Spedali Civili Brescia, Italy.
- 53 University of Salerno-AOU San Giovanni di Dio e Ruggi D'Aragona, Italy.
- 54 University of Foggia, Italy.
- 55 ASL CN1, Italy.
- 56 FPO IRCCS CANDIOLO, Italy.
- 57 Hospital Clínic. UB. Barcelona, Spain.
- 58 Hospital de la Santa Creu i Sant Pau, Spain.
- 59 Hospital Universitario de Gran Canaria Doctor Negrin, Spain.
- 60 Corporacio sanitaria Parc Tauli, Spain.
- 61 Fundacion Puigvert, Spain.
- 62 Hospital Universitario La Princesa, Spain.
- 63 University Hospital of Guadalajara, Spain.
- 64 Hospital Santa Maria, Spain.
- 65 Hospital Universitario Lucus Augusti, Spain.
- 66 Hospital Universitari Doctor Peset, Spain.
- 67 Hospital Arnau De Vilanova-Lliria, Spain.
- 68 Hospital Universitario Príncipe de Asturias, Spain.
- 69 Central Military University Emergency Hospital From Romania, Romania.
- 70 Regional Institute of Gastroenterology and Hepatology "Prof Dr Octavian Fodor" Cluj Napoca, Romania.
- 71 Fundeni Clinical Institute, Romania.
- 72 Constanta County Emergency Clinical Hospital, Romania.
- 73 Emergency county hospital cluj, Romania.
- 74 Spital Clinic Judetean de Urgenta Targu Mures, Romania.
- 75 Prof Dr Gerota Hospital, Romania.
- 76 Emergency Institute for CardioVascular Diseases Prof. Dr. C.C.Iliescu, Romania.
- 77 Kantonsspital St. Gallen, Switzerland.
- 78 Basel University Hospital, Switzerland.
- 79 Kantonsspital Winterthur, Switzerland.
- 80 University Hospital Zurich, Switzerland.
- 81 Hôpital du Valais, Switzerland.
- 82 Geneva University Hospitals, Switzerland.
- 83 Pomeranian Medical University, Poland.
- 84 Medical University of Silesia, Poland.
- 85 St John Grande Hospital, Poland.
- 86 Heliodor Swiecicki Clinical Hospital at Poznan University of Medical Sciences, Poland.
- 87 The University Hospital in Krakow, Poland.
- 88 St. Raphael Hospital, Poland.
- 89 Ankara University Medical School, Turkey.
- 90 Istanbul University Istanbul Faculty of Medicine, Turkey.
- 91 Ufuk University Faculty of Medicine, Turkey.
- 92 Kocaeli Derince Training and Research Hospital, Turkey.
- 93 Suleyman Demirel University School of Medicine, Turkey.
- 94 Ankara University School of Medicine Cebeci Hospital, Turkey.
- 95 Selcuk University Faculty of Medicine, Turkey.
- 96 Istanbul University- Cerrahpasa, Cerrahpasa Faculty of Medicine, Turkey.
- 97 Amsterdam UMC, location AMC, Amsterdam, Netherlands.
- 98 University Medical Center Utrecht, Netherlands.
- 99 Martini General Hospital Groningen, Netherlands.
- 100 University Medical Center Groningen (UMCG), Netherlands.
- 101 Maasstad Hospital, Netherlands.
- 102 Erasmus MC, Netherlands.
- 103 Hospital Beatriz Ângelo, Portugal.
- 104 Centro Hospitalar São João, Portugal.
- 105 Centro Hospitalar do Baixo Vouga, Portugal.
- 106 Centro Hospitalar de Vila Nova de Gaia / Espinho, Portugal.
- 107 Hospital de Santo Espírito da Ilha Terceira, E.P.E.R., Portugal.
- 108 Centro Hospitalar Entre Douro e Vouga, EPE, Portugal.
- 109 Hospital Central do Funchal, Portugal.
- 110 Hospital de Sta. Marta, CHLC, Portugal.
- 111 Hospital de Braga, Portugal.
- 112 General Hospital of Athens "G. Gennimatas", Greece.
- 113 General Hospital of Thessaloniki "Ippokratio", Greece.
- 114 Tzaneio General Hospital of Piraeus, Greece.
- 115 University Hospital of Patras, Greece.
- 116 Aretaieion University Hospital, Greece.
- 117 Ahepa University Hospital, Greece.
- 118 Wrightington, Wigan and Leigh NHS Foundation Trust, United Kingdom.
- 119 Guys and St Thomas NHS Foundation Trust, United Kingdom.
- 120 Royal Surrey NHS Foundation Trust, United Kingdom.
- 121 Royal Bolton Hospital, United Kingdom.
- 122 York Teaching Hospital, United Kingdom.
- 123 The Royal Oldham Hospital - The Pennine Acute Hospitals NHS Trust, United Kingdom.
- 124 Queen Victoria Hospital, United Kingdom.
- 125 Yeovil Hospital, United Kingdom.
- 126 Royal Bournemouth Hospital, United Kingdom.
- 127 Nottingham University Hospital, Queen's Medical Centre, United Kingdom.
- 128 St James' University Hospital, United Kingdom.
- 129 Stockport NHS Foundation Trust, United Kingdom.
- 130 Poole Hospital NHS Foundation Trust, United Kingdom.
- 131 Musgrove Park Hospital, United Kingdom.
- 132 Linköping University Hospital, Sweden.
- 133 Karolinska University Hospital and Karolinska Institutet, Sweden.
- 134 Sundsvall Hospital, Sweden.
- 135 Karolinska Institute Physiology and Pharmacology, Sweden.
- 136 Uppsala University Hospital, Sweden.
- 137 Uppsala University, Sweden.
- 138 Ghent University Hospital, Belgium.
- 139 Antwerp University Hospital, Belgium.
- 140 University Hospitals Leuven, Belgium.
- 141 CHU Saint-Pierre, Belgium.
- 142 P.A. Herzen Moscow Cancer Research Institute, Russia.
- 143 Moscow Regional Research Clinical Institute, Russia.
- 144 Privolzhskiy District Medical Center, Russia.
- 145 Krasnoyrask Regional Clinical Hospital; Professor V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Russia.
- 146 Clinic for Anesthesiology, Reanimation and Intensive Care medicine, Republic of North Macedonia.
- 147 GOB 8-mi Septemvri, Skopje, Republic of North Macedonia.
- 148 UK Dubrava, J.J. Strossmayer University of Osijek, Faculty of Medicine, Croatia.
- 149 University Medical Centre Ljubljana, Slovenia.
- 150 University Hospital Kaneff Ruse, Bulgaria.
- 151 Cardiovascular Institute Dedinje, Serbia.
- 152 Clinical Center Nis, Serbia.
- 153 Medical University of Vienna, Austria.
- 154 Klinikum Wels Grieskirchen, Austria.
- 155 Military Teaching Hospital Clermont Tonnerre, France.
- 156 Clinique du Millénaire, France.
- 157 Mater University Hospital, University College Dublin, Ireland.
- 158 Mater Dei Hospital, Malta.
- 159 University of Prishtina, Faculty of Medicine, Kosovo.
- PMID: 38336516
- DOI: 10.1016/j.bja.2023.12.036
Pathological findings associated with the updated European Society of Cardiology 2022 guidelines for preoperative cardiac testing: an observational cohort modelling study
Authors
Collaborators
-
MET-REPAIR investigators:
Johann Kemper 25 , Lena Kohaupt 25 , Jette Witzler 25 , Michael Tuzhikov 25 , Sebastian Roth 25 , Alexandra Stroda 25 , René M'Pembele 25 , Theresa Tenge 25 , Cornelia Schultze 26 , Nele Verbarg 26 , Christian Gehrke 26 , Anna Katharina Klemann 26 , Friederike Hagebölling 26 , Svenja Albrecht 27 , Jakob Stroeder 27 , Ann-Kristin Schubert 27 , Florian Espeter 28 , Benedikt Russe 28 , Markus A Weigand 28 , Lars Bergmann 29 , Matthias Unterberg 29 , Petra Bischoff 30 , Raphael Pirzer 31 , Patric Rene Rach 31 , Klaus Ott 31 , Alexander Zarbock 32 , Ana Kowark 33 , Claudia Neumann 34 , Bahareh Marchand 34 , Christoph Sponholz 35 , Henrik Rueffert 36 , Mira Kramer 37 , Kai Zacharowski 38 , Patrick Meybohm 38 , Simone Lindau 38 , Patrick Meybohm 39 , Melissa Carollo 40 , Cecilia Novazzi 40 , Fiorenza Toso 40 , Alessandro Bacuzzi 40 , Riccardo Ragazzi 41 , Carlo Alberto Volta 41 , Francesco De Giorgi 41 , Barbara Bacer 42 , Antonio Federico 42 , Davide Chiumello 43 , Luigi Vetrugno 44 , Alberto Castella 45 , Simonetta Tesoro 46 , Antonella Cotoia 47 , Elena Bignami 48 , Agrippino Bellissima 49 , Andrea Cortegiani 50 , Marco Crisman 51 , Arturo Toninelli 52 , Ornella Piazza 53 , Lucia Mirabella 54 , Matteo Bossolasco 55 , Francesco Bona 56 , Juan Manuel Perdomo 57 , Miquel Coca-Martinez 57 , Albert Carramiñana 57 , Marta Giné Servén 58 , Astrid Batalla González 58 , José Maria Gil Sánchez 58 , Ángel Becerra-Bolaños 59 , Aurelio Rodríguez-Pérez 59 , Anna Artigas Soler 60 , Morena Basso 60 , Anna Peig Font 60 , Diana Vernetta 61 , Julia Hernando Santos 62 , Enrique Alday Muñoz 62 , Mercedes Cabellos Olivares 63 , Gregorio Marco 64 , Maria Bermudez Lopez 65 , Javier Barrio 66 , María Isabel Forés 67 , Estefanía Boix 67 , Mercedes Ayuso 68 , Bogdan Sorel Petre 69 , Ioana Sorina Oprea 69 , Mihai Dan Latiș 69 , Simona Margarit 70 , Horatiu Vasian 70 , Dana Tomescu 71 , Iulia Cîndea 72 , Dan Sebastian Dirzu 73 , Sanda-Maria Copotoiu 74 , Alida Moise 75 , Serban Bubenek-Turconi 76 , Liana Valeanu 76 , Patrick Mark Wanner 77 , Mirjana Djurdjevic 77 , Sandra Nuth 77 , Esther Seeberger 78 , Nicolai Goettel 78 , Firmin Kamber 78 , Michael Thomas Ganter 79 , Thomas Jan Gerber 79 , Daniela Schneebeli 79 , Andreas Pregernig 80 , Sina Grape 81 , Simon Tomala 82 , Bernardo Bollen Pinto 82 , Maciej Żukowski 83 , Małgorzata Zegan-Barańska 83 , Igor Karolak 83 , Lukasz Krzych 84 , Szymon Czajka 84 , Dorota Studzińska 85 , Anna Kluzik 86 , Tomasz Koszel 86 , Izabela Pabjańczyk 87 , Anna Gajdosz 88 , Suheyla Karadag Erkoc 89 , Basak Ceyda Meco 89 , Ahmet Kemalettin Koltka 90 , Muserref Beril Dincer 90 , Perihan Ekmekçi 91 , Kemal Tolga Saracoglu 92 , Filiz Alkaya Solmaz 93 , Menekse Ozcelik 94 , Oguzhan Arun 95 , Ozlem Korkmaz Dilmen 96 , Benedikt Preckel 97 , Markus W Hollmann 97 , Yannick Hazen 98 , Hans Donald de Boer 99 , Anne Epema 100 , Seppe Koopman 101 , Felix Van Lier 102 , Rita Pinto 103 , André Carrão 103 , Daniel Ribeiro 103 , Joana Mourão 104 , Miguel Coelho 105 , Nuno Losa 106 , Nuno Santos 107 , Luis Cabral 107 , Diana Afonso 108 , Sérgio Zenha 109 , Cristina Ramos 110 , Carla Hipólito 111 , Maria Vasilaki 112 , Antonia Andreeva 112 , Donika Zaimi 113 , Athanasios Chalkias 114 , Maria Spyraki 115 , Martina Rekatsina 116 , Georgia Tsaousi 117 , Anthony Short 118 , Sonja Meier 119 , Thumuluru Kavitha Madhuri 120 , Scott Latham 121 , James Knock 122 , Andrew Drummond 123 , Fiona Ramsden 124 , Agnieszka Kubisz-Pudelko 125 , James Walker 126 , Iain Moppett 127 , Louise White 128 , Matthew Jackson 129 , Henrik Reschreiter 130 , Richard Innes 131 , Michelle Chew 132 , Sigridur Kalman 133 , Jakob Wallden 134 , Anna Schening 135 , Lina Jonikaite 136 , Anna Enlund 137 , Luc De Baerdemaeker 138 , Stuart Morrison 139 , Steffen Rex 140 , Alexandros Alexis 141 , Viktoria E Khoronenko 142 , Alexey Ovezov 143 , Vladislav Belskii 144 , Kseniya Kaznacheeva 144 , Alexey Gritsan 145 , Biljana Kuzmanovska 146 , Liljana Malinovska-Nikolovska 147 , Stjepan Barisin 148 , Peter Poredos 149 , Daniela Arabadzhieva 150 , Dragana Unic-Stojanovic 151 , Mladjan Golubović 152 , Edith Fleischmann 153 , Oskar Kotzinger 154 , Marc Danguy Des Deserts 155 , Nicolas Ducrocq 156 , Donal J Buggy 157 , Jean François Bonnet 157 , Barbara Cusack 157 , Paul Calleja 158 , Antigona Hasani 159 , Rajmonda Nallbani 159
Affiliations
- 1 Department of Anaesthesiology, University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf, Germany. Electronic address: Alexandra.stroda@med.uni-duesseldorf.de.
- 2 Clinic for Anaesthesia, Intermediate Care, Prehospital Emergency Medicine and Pain Therapy, University Hospital Basel, Basel, Switzerland.
- 3 Department of Anaesthesia and Intensive Care, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
- 4 Center for Intensive Care and Perioperative Medicine, Jagiellonian University Medical College, Kraków, Poland.
- 5 Department of Anaesthesiology and Peri-operative Medicine, Ghent University Hospital, Ghent University, Ghent, Belgium.
- 6 Division of Anaesthesiology, Intensive Care, Rescue and Pain Medicine, Kantonsspital St. Gallen, St. Gallen, Switzerland.
- 7 Institute of Anaesthesiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
- 8 Department of Translational Medicine, University of Ferrara, Ferrara, Italy.
- 9 Department of Anaesthesia, Hospital Clinic of Barcelona, Universidad de Barcelona, Barcelona, Spain.
- 10 Department of Anaesthesiology and Intensive Care Medicine, Klinik Hirslanden, Zurich, Switzerland.
- 11 Department of Anaesthesiology, Moscow Regional Research Clinical Institute, Moscow, Russia.
- 12 Department of Anaesthesiology and ICU, Ankara University Medical School, Ankara, Turkey.
- 13 Department of Anaesthesiology, University Medical Center Utrecht, Utrecht, The Netherlands.
- 14 Department of Anaesthesiology, Hospital Beatriz Ângelo, Loures, Portugal.
- 15 Aretaieion University Hospital National and Kapodistrian University of Athens, Athens, Greece.
- 16 Department of Perioperative Medicine and Intensive Care, Karolinska Hospital and Institution for Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.
- 17 Department of Anaesthesiology and Intensive Care Medicine, Hannover Medical School, Hannover, Germany.
- 18 Anesthesia and Intensive Care Department, University Hospital, Varese, Italy.
- 19 Department of Anaesthesiology, Intensive Therapy and Pain Management, Pomeranian Medical University, Szczecin, Poland.
- 20 Department of Anaesthesiology, Heidelberg University Hospital, Heidelberg, Germany.
- 21 Anesthesia and Intensive Care Department III, Carol Davila University of Medicine and Pharmacy Bucharest, Central Military Emergency University Hospital "Dr. Carol Davila Bucharest", Bucharest, Romania.
- 22 Department of Anaesthesiology, Mater University Hospital, Dublin, Ireland.
- 23 Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK.
- 24 Department of Anaesthesiology, University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf, Germany; CARID, Cardiovascular Research Institute Düsseldorf, Medical Faculty and University Hospital Düsseldorf, Heinrich-Heine University Düsseldorf, Düsseldorf, Germany.
- 25 Universitätsklinikum Düsseldorf, Germany.
- 26 Hannover Medical School, Germany.
- 27 University Hospital Marburg, Germany.
- 28 Heidelberg University Hospital, Germany.
- 29 University Hospital Knappschaftskrankenhaus Bochum, Germany.
- 30 Marien Hospital Herne, Ruhr University Bochum, Germany.
- 31 Universitätsklinikum Augsburg, Germany.
- 32 University Hospital Muenster, Germany.
- 33 University Hospital RWTH Aachen, Germany.
- 34 University Hospital Bonn, Germany.
- 35 Jena University Hospital, Germany.
- 36 Helios Klinik Schkeuditz, Germany.
- 37 University Witten / Herdecke - Hospital Center Merheim Cologne, Germany.
- 38 University Hospital Frankfurt, Germany.
- 39 University Hospital Würzburg, Germany.
- 40 ASST Settelaghi - Ospedale di Circolo e Fondazione Macchi, Varese, Italy.
- 41 Arcispedale Sant'Anna Ferrara, Italy.
- 42 Azienda USL Di Bologna, Italy.
- 43 ASST Santi Paolo e Carlo, Italy.
- 44 Asuiud, Italy.
- 45 Ospedale San Raffaele IRCCS, Italy.
- 46 University of Perugia Hospital Santa Maria della Misericordia, Italy.
- 47 Hospital of Foggia, Italy.
- 48 Azienda Ospedaliero universitaria di Parma, Italy.
- 49 Arnas Garibaldi, Italy.
- 50 University Hospital Policlinico P. Giaccone, Italy.
- 51 Azienda Sanitaria Universitaria Integrata di Trieste, Italy.
- 52 ASST Spedali Civili Brescia, Italy.
- 53 University of Salerno-AOU San Giovanni di Dio e Ruggi D'Aragona, Italy.
- 54 University of Foggia, Italy.
- 55 ASL CN1, Italy.
- 56 FPO IRCCS CANDIOLO, Italy.
- 57 Hospital Clínic. UB. Barcelona, Spain.
- 58 Hospital de la Santa Creu i Sant Pau, Spain.
- 59 Hospital Universitario de Gran Canaria Doctor Negrin, Spain.
- 60 Corporacio sanitaria Parc Tauli, Spain.
- 61 Fundacion Puigvert, Spain.
- 62 Hospital Universitario La Princesa, Spain.
- 63 University Hospital of Guadalajara, Spain.
- 64 Hospital Santa Maria, Spain.
- 65 Hospital Universitario Lucus Augusti, Spain.
- 66 Hospital Universitari Doctor Peset, Spain.
- 67 Hospital Arnau De Vilanova-Lliria, Spain.
- 68 Hospital Universitario Príncipe de Asturias, Spain.
- 69 Central Military University Emergency Hospital From Romania, Romania.
- 70 Regional Institute of Gastroenterology and Hepatology "Prof Dr Octavian Fodor" Cluj Napoca, Romania.
- 71 Fundeni Clinical Institute, Romania.
- 72 Constanta County Emergency Clinical Hospital, Romania.
- 73 Emergency county hospital cluj, Romania.
- 74 Spital Clinic Judetean de Urgenta Targu Mures, Romania.
- 75 Prof Dr Gerota Hospital, Romania.
- 76 Emergency Institute for CardioVascular Diseases Prof. Dr. C.C.Iliescu, Romania.
- 77 Kantonsspital St. Gallen, Switzerland.
- 78 Basel University Hospital, Switzerland.
- 79 Kantonsspital Winterthur, Switzerland.
- 80 University Hospital Zurich, Switzerland.
- 81 Hôpital du Valais, Switzerland.
- 82 Geneva University Hospitals, Switzerland.
- 83 Pomeranian Medical University, Poland.
- 84 Medical University of Silesia, Poland.
- 85 St John Grande Hospital, Poland.
- 86 Heliodor Swiecicki Clinical Hospital at Poznan University of Medical Sciences, Poland.
- 87 The University Hospital in Krakow, Poland.
- 88 St. Raphael Hospital, Poland.
- 89 Ankara University Medical School, Turkey.
- 90 Istanbul University Istanbul Faculty of Medicine, Turkey.
- 91 Ufuk University Faculty of Medicine, Turkey.
- 92 Kocaeli Derince Training and Research Hospital, Turkey.
- 93 Suleyman Demirel University School of Medicine, Turkey.
- 94 Ankara University School of Medicine Cebeci Hospital, Turkey.
- 95 Selcuk University Faculty of Medicine, Turkey.
- 96 Istanbul University- Cerrahpasa, Cerrahpasa Faculty of Medicine, Turkey.
- 97 Amsterdam UMC, location AMC, Amsterdam, Netherlands.
- 98 University Medical Center Utrecht, Netherlands.
- 99 Martini General Hospital Groningen, Netherlands.
- 100 University Medical Center Groningen (UMCG), Netherlands.
- 101 Maasstad Hospital, Netherlands.
- 102 Erasmus MC, Netherlands.
- 103 Hospital Beatriz Ângelo, Portugal.
- 104 Centro Hospitalar São João, Portugal.
- 105 Centro Hospitalar do Baixo Vouga, Portugal.
- 106 Centro Hospitalar de Vila Nova de Gaia / Espinho, Portugal.
- 107 Hospital de Santo Espírito da Ilha Terceira, E.P.E.R., Portugal.
- 108 Centro Hospitalar Entre Douro e Vouga, EPE, Portugal.
- 109 Hospital Central do Funchal, Portugal.
- 110 Hospital de Sta. Marta, CHLC, Portugal.
- 111 Hospital de Braga, Portugal.
- 112 General Hospital of Athens "G. Gennimatas", Greece.
- 113 General Hospital of Thessaloniki "Ippokratio", Greece.
- 114 Tzaneio General Hospital of Piraeus, Greece.
- 115 University Hospital of Patras, Greece.
- 116 Aretaieion University Hospital, Greece.
- 117 Ahepa University Hospital, Greece.
- 118 Wrightington, Wigan and Leigh NHS Foundation Trust, United Kingdom.
- 119 Guys and St Thomas NHS Foundation Trust, United Kingdom.
- 120 Royal Surrey NHS Foundation Trust, United Kingdom.
- 121 Royal Bolton Hospital, United Kingdom.
- 122 York Teaching Hospital, United Kingdom.
- 123 The Royal Oldham Hospital - The Pennine Acute Hospitals NHS Trust, United Kingdom.
- 124 Queen Victoria Hospital, United Kingdom.
- 125 Yeovil Hospital, United Kingdom.
- 126 Royal Bournemouth Hospital, United Kingdom.
- 127 Nottingham University Hospital, Queen's Medical Centre, United Kingdom.
- 128 St James' University Hospital, United Kingdom.
- 129 Stockport NHS Foundation Trust, United Kingdom.
- 130 Poole Hospital NHS Foundation Trust, United Kingdom.
- 131 Musgrove Park Hospital, United Kingdom.
- 132 Linköping University Hospital, Sweden.
- 133 Karolinska University Hospital and Karolinska Institutet, Sweden.
- 134 Sundsvall Hospital, Sweden.
- 135 Karolinska Institute Physiology and Pharmacology, Sweden.
- 136 Uppsala University Hospital, Sweden.
- 137 Uppsala University, Sweden.
- 138 Ghent University Hospital, Belgium.
- 139 Antwerp University Hospital, Belgium.
- 140 University Hospitals Leuven, Belgium.
- 141 CHU Saint-Pierre, Belgium.
- 142 P.A. Herzen Moscow Cancer Research Institute, Russia.
- 143 Moscow Regional Research Clinical Institute, Russia.
- 144 Privolzhskiy District Medical Center, Russia.
- 145 Krasnoyrask Regional Clinical Hospital; Professor V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Russia.
- 146 Clinic for Anesthesiology, Reanimation and Intensive Care medicine, Republic of North Macedonia.
- 147 GOB 8-mi Septemvri, Skopje, Republic of North Macedonia.
- 148 UK Dubrava, J.J. Strossmayer University of Osijek, Faculty of Medicine, Croatia.
- 149 University Medical Centre Ljubljana, Slovenia.
- 150 University Hospital Kaneff Ruse, Bulgaria.
- 151 Cardiovascular Institute Dedinje, Serbia.
- 152 Clinical Center Nis, Serbia.
- 153 Medical University of Vienna, Austria.
- 154 Klinikum Wels Grieskirchen, Austria.
- 155 Military Teaching Hospital Clermont Tonnerre, France.
- 156 Clinique du Millénaire, France.
- 157 Mater University Hospital, University College Dublin, Ireland.
- 158 Mater Dei Hospital, Malta.
- 159 University of Prishtina, Faculty of Medicine, Kosovo.
- PMID: 38336516
- DOI: 10.1016/j.bja.2023.12.036
Abstract
Background: In 2022, the European Society of Cardiology updated guidelines for preoperative evaluation. The aims of this study were to quantify: (1) the impact of the updated recommendations on the yield of pathological findings compared with the previous guidelines published in 2014; (2) the impact of preoperative B-type natriuretic peptide (NT-proBNP) use for risk estimation on the yield of pathological findings; and (3) the association between 2022 guideline adherence and outcomes.
Methods: This was a secondary analysis of MET-REPAIR, an international, prospective observational cohort study (NCT03016936). Primary endpoints were reduced ejection fraction (EF<40%), stress-induced ischaemia, and major adverse cardiovascular events (MACE). The explanatory variables were class of recommendations for transthoracic echocardiography (TTE), stress imaging, and guideline adherence. We conducted second-order Monte Carlo simulations and multivariable regression.
Results: In total, 15,529 patients (39% female, median age 72 [inter-quartile range: 67-78] yr) were included. The 2022 update changed the recommendation for preoperative TTE in 39.7% patients, and for preoperative stress imaging in 12.9% patients. The update resulted in missing 1 EF <40% every 3 fewer conducted TTE, and in 4 additional stress imaging per 1 additionally detected ischaemia events. For cardiac stress testing, four more investigations were performed for every 1 additionally detected ischaemia episodes. Use of NT-proBNP did not improve the yield of pathological findings. Multivariable regression analysis failed to find an association between adherence to the updated guidelines and MACE.
Conclusions: The 2022 update for preoperative cardiac testing resulted in a relevant increase in tests receiving a stronger recommendation. The updated recommendations for TTE did not improve the yield of pathological cardiac testing.
Keywords: NT-proBNP; echocardiography; ejection fraction; guideline adherence; major adverse cardiovascular events; perioperative medicine; stress echocardiography.
Copyright © 2024 British Journal of Anaesthesia. Published by Elsevier Ltd. All rights reserved.
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